5jcq
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21== | |
- | + | <StructureSection load='5jcq' size='340' side='right' caption='[[5jcq]], [[Resolution|resolution]] 1.60Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5jcq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JCQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JCQ FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jcq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jcq OCA], [http://pdbe.org/5jcq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jcq RCSB], [http://www.ebi.ac.uk/pdbsum/5jcq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jcq ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Ernst, B]] | ||
+ | [[Category: Jakob, R P]] | ||
+ | [[Category: Maier, T]] | ||
+ | [[Category: Rabbani, S]] | ||
+ | [[Category: Bladder infection]] | ||
+ | [[Category: Carbohydrate]] | ||
+ | [[Category: Fimh]] | ||
+ | [[Category: Lectin]] | ||
+ | [[Category: Mannose]] | ||
+ | [[Category: Sugar binding protein]] | ||
+ | [[Category: Type 1 pilus]] | ||
+ | [[Category: Uti]] |
Revision as of 12:56, 10 May 2017
Crystal structure of the FimH lectin domain from E.coli K12 in complex with methyl alpha-D-mannopyrannoside in spacegroup P21
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Categories: Ernst, B | Jakob, R P | Maier, T | Rabbani, S | Bladder infection | Carbohydrate | Fimh | Lectin | Mannose | Sugar binding protein | Type 1 pilus | Uti