5v5i

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m (Protected "5v5i" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5v5i is ON HOLD until Paper Publication
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==OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1==
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<StructureSection load='5v5i' size='340' side='right' caption='[[5v5i]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5v5i]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V5I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V5I FirstGlance]. <br>
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Description:
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSX:S-OXY+CYSTEINE'>CSX</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5v5g|5v5g]], [[5v5h|5v5h]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v5i OCA], [http://pdbe.org/5v5i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v5i RCSB], [http://www.ebi.ac.uk/pdbsum/5v5i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v5i ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/L_CCHFI L_CCHFI]] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity.
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__TOC__
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</StructureSection>
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[[Category: Khare, B]]
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[[Category: Mark, B L]]
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[[Category: Deubiquitinase]]
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[[Category: Hydrolase]]
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[[Category: Ovarian tumor domain protease]]
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[[Category: Transferase]]
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[[Category: Ubiquitin variant]]

Revision as of 13:02, 10 May 2017

OTU protease of Crimean Congo Hemorrhagic Fever Virus bound to ubiquitin variant CC.1

5v5i, resolution 2.20Å

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