5meb
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of yeast Cdt1 C-terminal domain== | |
- | + | <StructureSection load='5meb' size='340' side='right' caption='[[5meb]], [[Resolution|resolution]] 1.80Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[5meb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MEB FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5meb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5meb OCA], [http://pdbe.org/5meb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5meb RCSB], [http://www.ebi.ac.uk/pdbsum/5meb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5meb ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CDT1_YEAST CDT1_YEAST]] DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.<ref>PMID:11560884</ref> <ref>PMID:11967159</ref> <ref>PMID:16387651</ref> <ref>PMID:16824194</ref> <ref>PMID:17825064</ref> <ref>PMID:18006685</ref> <ref>PMID:19896182</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Cherepanov, P]] | ||
+ | [[Category: Diffley, J F.X]] | ||
[[Category: Frigola, J]] | [[Category: Frigola, J]] | ||
- | [[Category: | + | [[Category: Pye, V E]] |
- | [[Category: | + | [[Category: Cdt1]] |
+ | [[Category: Cell cycle]] | ||
+ | [[Category: Dna replication]] | ||
+ | [[Category: Mcm]] | ||
+ | [[Category: Winged helix]] | ||
+ | [[Category: Yeast]] |
Revision as of 15:48, 17 May 2017
Crystal structure of yeast Cdt1 C-terminal domain
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Categories: Cherepanov, P | Diffley, J F.X | Frigola, J | Pye, V E | Cdt1 | Cell cycle | Dna replication | Mcm | Winged helix | Yeast