5nt7
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of Vasa== | |
| - | + | <StructureSection load='5nt7' size='340' side='right' caption='[[5nt7]], [[Resolution|resolution]] 1.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5nt7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NT7 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA_helicase RNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.13 3.6.4.13] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nt7 OCA], [http://pdbe.org/5nt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nt7 RCSB], [http://www.ebi.ac.uk/pdbsum/5nt7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nt7 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/VASA1_DROME VASA1_DROME]] Involved in translational control mechanisms operating in early stages of oogenesis. Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts. Essential for the formation and/or structural integrity of perinuclear nuage particles during germ cell formation. Required for gus, Fsn and aub accumulation at the posterior pole of the embryo. Required for the localization of vas to the perinuclear region of nurse cells.<ref>PMID:10678180</ref> <ref>PMID:11526087</ref> <ref>PMID:12479811</ref> <ref>PMID:14588248</ref> <ref>PMID:16630817</ref> <ref>PMID:18590813</ref> <ref>PMID:20123973</ref> <ref>PMID:3052853</ref> <ref>PMID:3140040</ref> <ref>PMID:8026330</ref> <ref>PMID:9521895</ref> [[http://www.uniprot.org/uniprot/OSKA_DROME OSKA_DROME]] Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole.<ref>PMID:1641021</ref> <ref>PMID:2070416</ref> <ref>PMID:2070417</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: RNA helicase]] | ||
| + | [[Category: Ephrussi, A]] | ||
| + | [[Category: Jeske, M]] | ||
| + | [[Category: Mueller, C W]] | ||
| + | [[Category: Atpase]] | ||
| + | [[Category: Dead-box rna helicase]] | ||
| + | [[Category: Germ plasm]] | ||
| + | [[Category: Hydrolase- hydrolase regulator complex]] | ||
| + | [[Category: Hydrolase-hydrolase regulator complex]] | ||
| + | [[Category: Lotus]] | ||
| + | [[Category: Nuage]] | ||
| + | [[Category: Regulator]] | ||
| + | [[Category: Rna binding]] | ||
| + | [[Category: Stimulator]] | ||
Revision as of 15:49, 17 May 2017
Structure of the LOTUS domain of Oskar in complex with the C-terminal RecA-like domain of Vasa
| |||||||||||
