5ugh

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'''Unreleased structure'''
 
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The entry 5ugh is ON HOLD until Paper Publication
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==Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366==
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<StructureSection load='5ugh' size='340' side='right' caption='[[5ugh]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ugh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UGH FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8AJ:(E)-2-(7-CHLORO-5-PHENYL[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-YL)-N,N-DIMETHYLETHEN-1-AMINE'>8AJ</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ugh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ugh OCA], [http://pdbe.org/5ugh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ugh RCSB], [http://www.ebi.ac.uk/pdbsum/5ugh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ugh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN]] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
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__TOC__
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</StructureSection>
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[[Category: Methionine adenosyltransferase]]
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[[Category: Feng, J]]
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[[Category: Kaiser, S E]]
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[[Category: Stewart, A E]]
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[[Category: Mat2a]]
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[[Category: Sam]]
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[[Category: Transferase]]

Revision as of 15:50, 17 May 2017

Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366

5ugh, resolution 2.06Å

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