5vex
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the human GLP-1 receptor complex with NNC0640== | |
| - | + | <StructureSection load='5vex' size='340' side='right' caption='[[5vex]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5vex]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VEX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VEX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97V:4-{[(4-CYCLOHEXYLPHENYL){[3-(METHYLSULFONYL)PHENYL]CARBAMOYL}AMINO]METHYL}-N-(1H-TETRAZOL-5-YL)BENZAMIDE'>97V</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vew|5vew]]</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vex OCA], [http://pdbe.org/5vex PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vex RCSB], [http://www.ebi.ac.uk/pdbsum/5vex PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vex ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lysozyme]] | ||
| + | [[Category: Cai, X]] | ||
| + | [[Category: Dai, A]] | ||
| + | [[Category: Graaf, C D]] | ||
| + | [[Category: Han, G W]] | ||
| + | [[Category: Hanson, M A]] | ||
| + | [[Category: Jiang, S]] | ||
| + | [[Category: Lau, J]] | ||
| + | [[Category: Lin, G]] | ||
| + | [[Category: Liu, D]] | ||
| + | [[Category: Liu, K]] | ||
| + | [[Category: Liu, Z J]] | ||
| + | [[Category: Song, G]] | ||
| + | [[Category: Stevens, R C]] | ||
| + | [[Category: Wang, M W]] | ||
| + | [[Category: Wang, Y]] | ||
| + | [[Category: Wu, B]] | ||
| + | [[Category: Wu, F]] | ||
| + | [[Category: Wu, Y]] | ||
| + | [[Category: Yang, D]] | ||
| + | [[Category: Ye, L]] | ||
| + | [[Category: Zhao, S]] | ||
| + | [[Category: Zhou, Q]] | ||
| + | [[Category: 7tm domain]] | ||
| + | [[Category: Class b]] | ||
| + | [[Category: Gpcr]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Treatment of type 2 diabetes]] | ||
Revision as of 15:50, 17 May 2017
Structure of the human GLP-1 receptor complex with NNC0640
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Categories: Lysozyme | Cai, X | Dai, A | Graaf, C D | Han, G W | Hanson, M A | Jiang, S | Lau, J | Lin, G | Liu, D | Liu, K | Liu, Z J | Song, G | Stevens, R C | Wang, M W | Wang, Y | Wu, B | Wu, F | Wu, Y | Yang, D | Ye, L | Zhao, S | Zhou, Q | 7tm domain | Class b | Gpcr | Signaling protein | Treatment of type 2 diabetes
