4zyc
From Proteopedia
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==Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5== | ==Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5== | ||
<StructureSection load='4zyc' size='340' side='right' caption='[[4zyc]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='4zyc' size='340' side='right' caption='[[4zyc]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
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<table><tr><td colspan='2'>[[4zyc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZYC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZYC FirstGlance]. <br> | <table><tr><td colspan='2'>[[4zyc]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZYC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZYC FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SS:(S)-2-(2-((2H-TETRAZOL-5-YL)METHOXY)-4-METHYLPHENYL)-1-(4-CHLOROPHENYL)-6,7-DIETHOXY-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE'>4SS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4SS:(S)-2-(2-((2H-TETRAZOL-5-YL)METHOXY)-4-METHYLPHENYL)-1-(4-CHLOROPHENYL)-6,7-DIETHOXY-1,2-DIHYDROISOQUINOLIN-3(4H)-ONE'>4SS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zyc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zyc RCSB], [http://www.ebi.ac.uk/pdbsum/4zyc PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zyc OCA], [http://pdbe.org/4zyc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zyc RCSB], [http://www.ebi.ac.uk/pdbsum/4zyc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zyc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4zyc" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 16:06, 17 May 2017
Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5
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