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| - | | + | #REDIRECT [[5vsv]] This PDB entry is obsolete and replaced by 5vsv |
| - | ==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225==
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| - | <StructureSection load='5uzo' size='340' side='right' caption='[[5uzo]], [[Resolution|resolution]] 2.21Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[5uzo]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZO FirstGlance]. <br>
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| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8Q4:2-CHLORO-5-[({2-[3-(PROP-1-EN-2-YL)PHENYL]PROPAN-2-YL}CARBAMOYL)AMINO]PHENYL+HYDROGEN+CARBONATE'>8Q4</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
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| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q32|4q32]], [[4q33|4q33]], [[5uwx|5uwx]], [[5uxe|5uxe]], [[5uze|5uze]], [[5uzc|5uzc]], [[5uzs|5uzs]]</td></tr>
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5uzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5uzo OCA], [http://pdbe.org/5uzo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5uzo RCSB], [http://www.ebi.ac.uk/pdbsum/5uzo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5uzo ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Anderson, W F]]
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| - | [[Category: Structural genomic]]
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| - | [[Category: Gollapalli, D R]]
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| - | [[Category: Gu, M]]
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| - | [[Category: Hedstrom, L]]
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| - | [[Category: Joachimiak, A]]
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| - | [[Category: Kim, Y]]
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| - | [[Category: Makowska-Grzyska, M]]
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| - | [[Category: Maltseva, N]]
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| - | [[Category: Mulligan, R]]
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| - | [[Category: Csgid]]
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| - | [[Category: Impdh]]
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| - | [[Category: Oxidoreductase]]
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| - | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
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| - | [[Category: Tim barrel]]
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