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5u0j

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'''Unreleased structure'''
 
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The entry 5u0j is ON HOLD
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==C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form==
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<StructureSection load='5u0j' size='340' side='right' caption='[[5u0j]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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Authors: Pascoal, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5u0j]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5U0J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5U0J FirstGlance]. <br>
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Description: C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) -monoclinic crystal form
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u0i|5u0i]], [[5u0k|5u0k]]</td></tr>
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[[Category: Pascoal, C.C]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutaminase Glutaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.2 3.5.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5u0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5u0j OCA], [http://pdbe.org/5u0j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5u0j RCSB], [http://www.ebi.ac.uk/pdbsum/5u0j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5u0j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN]] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.
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__TOC__
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</StructureSection>
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[[Category: Glutaminase]]
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[[Category: Ambrosio, A L.B]]
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[[Category: Dias, S M.G]]
[[Category: Gonzalez, A]]
[[Category: Gonzalez, A]]
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[[Category: Dias, S.M.G]]
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[[Category: Pascoal, C C]]
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[[Category: Ambrosio, A.L.B]]
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[[Category: Ankyrin]]
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[[Category: Gls1]]
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[[Category: Human]]
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[[Category: Hydrolase]]

Revision as of 13:49, 24 May 2017

C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - monoclinic crystal form

5u0j, resolution 1.72Å

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