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5xez
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the Full-length glucagon class B G protein-coupled receptor== | |
| - | + | <StructureSection load='5xez' size='340' side='right' caption='[[5xez]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xez]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XEZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97V:4-{[(4-CYCLOHEXYLPHENYL){[3-(METHYLSULFONYL)PHENYL]CARBAMOYL}AMINO]METHYL}-N-(1H-TETRAZOL-5-YL)BENZAMIDE'>97V</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xf1|5xf1]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xez OCA], [http://pdbe.org/5xez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xez RCSB], [http://www.ebi.ac.uk/pdbsum/5xez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xez ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN]] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Lysozyme]] | ||
| + | [[Category: Cai, X]] | ||
| + | [[Category: Cherezov, V]] | ||
| + | [[Category: Dai, A]] | ||
| + | [[Category: Dharmarajan, V]] | ||
| + | [[Category: Dong, Y]] | ||
| + | [[Category: Geng, Z]] | ||
| + | [[Category: Graaf, C de]] | ||
| + | [[Category: Grant, T]] | ||
| + | [[Category: Griffin, P]] | ||
| + | [[Category: Han, G Y]] | ||
| + | [[Category: Hanson, M]] | ||
| + | [[Category: Jiang, H]] | ||
| + | [[Category: Lau, J]] | ||
| + | [[Category: Lin, G]] | ||
| + | [[Category: Liu, W]] | ||
| + | [[Category: Ma, L]] | ||
| + | [[Category: Nelson, G]] | ||
| + | [[Category: Qiao, A]] | ||
| + | [[Category: Reedtz-Runge, S]] | ||
| + | [[Category: Sierra, R]] | ||
| + | [[Category: Song, G]] | ||
| + | [[Category: Stevens, R]] | ||
| + | [[Category: Wang, M]] | ||
| + | [[Category: Weierstall, U]] | ||
| + | [[Category: Wu, B]] | ||
| + | [[Category: Wu, X]] | ||
| + | [[Category: Wu, Y]] | ||
| + | [[Category: Yang, D]] | ||
| + | [[Category: Yang, H]] | ||
| + | [[Category: Yang, L]] | ||
| + | [[Category: Zhang, H]] | ||
| + | [[Category: Zhao, Q]] | ||
| + | [[Category: 7tm domain]] | ||
| + | [[Category: Class b]] | ||
| + | [[Category: Human gcgr receptor]] | ||
| + | [[Category: Lcp]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Xfel]] | ||
Revision as of 13:53, 24 May 2017
Structure of the Full-length glucagon class B G protein-coupled receptor
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Categories: Lysozyme | Cai, X | Cherezov, V | Dai, A | Dharmarajan, V | Dong, Y | Geng, Z | Graaf, C de | Grant, T | Griffin, P | Han, G Y | Hanson, M | Jiang, H | Lau, J | Lin, G | Liu, W | Ma, L | Nelson, G | Qiao, A | Reedtz-Runge, S | Sierra, R | Song, G | Stevens, R | Wang, M | Weierstall, U | Wu, B | Wu, X | Wu, Y | Yang, D | Yang, H | Yang, L | Zhang, H | Zhao, Q | 7tm domain | Class b | Human gcgr receptor | Lcp | Membrane | Signaling protein | Xfel
