Gp41
From Proteopedia
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| + | <StructureSection load='1aik' size='340' side='right' caption='Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]].' scene=''> | ||
== Function == | == Function == | ||
'''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins]]. | '''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins]]. | ||
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== Relevance == | == Relevance == | ||
Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell<ref>PMID:15180542</ref>. | Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the HIV-1 virus to the cell<ref>PMID:15180542</ref>. | ||
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== 3D Structures of Gp41 == | == 3D Structures of Gp41 == | ||
Revision as of 09:27, 4 June 2017
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3D Structures of Gp41
Updated on 04-June-2017
