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Hemolysin
From Proteopedia
(Difference between revisions)
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<StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''> | <StructureSection load='7ahl' size='350' side='right' caption='α-hemolysin heptamer (PDB code [[7ahl]]).' scene=''> | ||
== Function == | == Function == | ||
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**[[3anz]], [[7ahl]] – SaHL-α – ''Staphylococcus aureus''<br /> | **[[3anz]], [[7ahl]] – SaHL-α – ''Staphylococcus aureus''<br /> | ||
A full page in Proteopedia exploring [[7ahl]] is found [[Pore_forming_toxin,_α-hemolsyin|here]].<br/> | A full page in Proteopedia exploring [[7ahl]] is found [[Pore_forming_toxin,_α-hemolsyin|here]].<br/> | ||
| - | **[[3m2l]], [[3m4d]], [[4p24]] - SaHL-α (mutant)<br /> | + | **[[3m2l]], [[3m4d]], [[4p24]], [[4yhd]] - SaHL-α (mutant)<br /> |
**[[3m3r]], [[3m4e]] - SaHL-α (mutant) + β-cyclodextrin<br /> | **[[3m3r]], [[3m4e]] - SaHL-α (mutant) + β-cyclodextrin<br /> | ||
**[[4idj]], [[4u6v]] - SaHL-α + antibody<br /> | **[[4idj]], [[4u6v]] - SaHL-α + antibody<br /> | ||
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**[[3a57]] – HL 2 – ''Vibrio parahaemolyticus''<br /> | **[[3a57]] – HL 2 – ''Vibrio parahaemolyticus''<br /> | ||
**[[3hvn]] – HL (mutant) – ''Streptococcus suis''<br /> | **[[3hvn]] – HL (mutant) – ''Streptococcus suis''<br /> | ||
| - | **[[3fy3]] – | + | **[[3fy3]], [[5keh]], [[5kf3]], [[4w8q]] – PmHL A residues 30-265 – ''Proteus mirabilis''<br /> |
| + | **[[5sz8]], [[5kkd]], [[4w8r]], [[4w8s]], [[4w8t]] - PmHL A residues 30-234 (mutant)<br /> | ||
| + | **[[1mt0]] – EcHL B ATP-binding domain – ''Escherichia coli''<br /> | ||
| + | **[[5c21]], [[5c22]] - EcHL D residues 57-333 <br /> | ||
**[[2wcd]] – EcHL E residues 2-303 – ''Escherichia coli''<br /> | **[[2wcd]] – EcHL E residues 2-303 – ''Escherichia coli''<br /> | ||
**[[1qoy]], [[4pho]], [[4phq]] - EcHL E (mutant)<br /> | **[[1qoy]], [[4pho]], [[4phq]] - EcHL E (mutant)<br /> | ||
| - | **[[1mt0]] – EcHL B ATP-binding domain<br /> | ||
**[[2oai]], [[2r8d]] – HL corc_hlyc domain – ''Xylella fastidiosa''<br /> | **[[2oai]], [[2r8d]] – HL corc_hlyc domain – ''Xylella fastidiosa''<br /> | ||
**[[2r2z]] – HL residues 346-435 – ''Enterococcus faecalis''<br /> | **[[2r2z]] – HL residues 346-435 – ''Enterococcus faecalis''<br /> | ||
| + | **[[4wx3]], [[4wx5]] - HL – ''Grimontia hollisae''<br /> | ||
*Alpha-toxin | *Alpha-toxin | ||
Revision as of 08:16, 12 June 2017
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3D Structures of hemolysin
Updated on 12-June-2017
A full page in Proteopedia exploring 7ahl is found here.
References
- ↑ Mestre MB, Fader CM, Sola C, Colombo MI. Alpha-hemolysin is required for the activation of the autophagic pathway in Staphylococcus aureus-infected cells. Autophagy. 2010 Jan;6(1):110-25. PMID:20110774
- ↑ Nizet V. Streptococcal beta-hemolysins: genetics and role in disease pathogenesis. Trends Microbiol. 2002 Dec;10(12):575-80. PMID:12564994
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