Survivin
From Proteopedia
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IAP4 is found in human cancer cells<ref>PMID:18032822</ref>. and can serve as a cancer marker and as a target for chemotherapy<ref>PMID:22680927</ref>. | IAP4 is found in human cancer cells<ref>PMID:18032822</ref>. and can serve as a cancer marker and as a target for chemotherapy<ref>PMID:22680927</ref>. | ||
| - | *<scene name='59/596423/Cv/4'>Human survivin interactions with histone H3 peptide</scene>. | + | *<scene name='59/596423/Cv/4'>Human survivin interactions with histone H3 peptide</scene> (PDB code [[3uig]]). |
| + | *<scene name='59/596423/Cv/5'>Zn coordination site in the human survivin</scene> (PDB code [[3uig]]). | ||
</StructureSection> | </StructureSection> | ||
Revision as of 10:22, 14 June 2017
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3D structures of survivin
Updated on 14-June-2017
References
- ↑ Tamm I, Wang Y, Sausville E, Scudiero DA, Vigna N, Oltersdorf T, Reed JC. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 1998 Dec 1;58(23):5315-20. PMID:9850056
- ↑ Carmena M, Wheelock M, Funabiki H, Earnshaw WC. The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol. 2012 Dec;13(12):789-803. doi: 10.1038/nrm3474. PMID:23175282 doi:http://dx.doi.org/10.1038/nrm3474
- ↑ Zaffaroni N, Costa A, Pennati M, De Marco C, Affini E, Madeo M, Erdas R, Cabras A, Kusamura S, Baratti D, Deraco M, Daidone MG. Survivin is highly expressed and promotes cell survival in malignant peritoneal mesothelioma. Cell Oncol. 2007;29(6):453-66. PMID:18032822
- ↑ Rodel F, Sprenger T, Kaina B, Liersch T, Rodel C, Fulda S, Hehlgans S. Survivin as a prognostic/predictive marker and molecular target in cancer therapy. Curr Med Chem. 2012;19(22):3679-88. PMID:22680927
