Pseudouridine synthase

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<StructureSection load='1ze2' size='400' side='right' caption='tRNA pseudouridine synthase complex with RNA and pseudouridine monophosphate [[1ze2]]' scene='46/465439/Cv/1' pspeed='8'>
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<StructureSection load='1ze2' size='340' side='right' caption='tRNA pseudouridine synthase complex with RNA and pseudouridine monophosphate [[1ze2]]' scene=''>
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== Function ==
== Function ==
'''tRNA pseudouridine synthase''' (PUS) catalyzes the conversion of tRNA uridine to tRNA pseudouridine<ref>PMID:14566049</ref>. PUS are active in the ribosomal large subunit (Rlu) and ribosomal small subunit (Rsu). '''Probable tRNA pseudouridine synthase''' (PPUS) is a similar enzyme.
'''tRNA pseudouridine synthase''' (PUS) catalyzes the conversion of tRNA uridine to tRNA pseudouridine<ref>PMID:14566049</ref>. PUS are active in the ribosomal large subunit (Rlu) and ribosomal small subunit (Rsu). '''Probable tRNA pseudouridine synthase''' (PPUS) is a similar enzyme.

Revision as of 11:28, 6 July 2017

tRNA pseudouridine synthase complex with RNA and pseudouridine monophosphate 1ze2

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3D Structures of tRNA pseudouridine synthase

Updated on 06-July-2017

References

  1. Pan H, Agarwalla S, Moustakas DT, Finer-Moore J, Stroud RM. Structure of tRNA pseudouridine synthase TruB and its RNA complex: RNA recognition through a combination of rigid docking and induced fit. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12648-53. Epub 2003 Oct 17. PMID:14566049 doi:10.1073/pnas.2135585100
  2. Phannachet K, Huang RH. Conformational change of pseudouridine 55 synthase upon its association with RNA substrate. Nucleic Acids Res. 2004 Feb 27;32(4):1422-9. Print 2004. PMID:14990747 doi:10.1093/nar/gkh287
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