MECDP synthase
From Proteopedia
(Difference between revisions)
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**[[3re3]] - MECPS – ''Francisella tularensis''<br /> | **[[3re3]] - MECPS – ''Francisella tularensis''<br /> | ||
**[[4c82]] - PfMECPS (mutant) + Zn – ''Plasmodium falciparum''<br /> | **[[4c82]] - PfMECPS (mutant) + Zn – ''Plasmodium falciparum''<br /> | ||
| + | **[[5iwx]] - BsMECPS + Mg – ''Bacillus subtilis''<br /> | ||
*MECPS binary complex | *MECPS binary complex | ||
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**[[4c81]] - PfMECPS (mutant) + CDP + Zn <br /> | **[[4c81]] - PfMECPS (mutant) + CDP + Zn <br /> | ||
**[[3fpi]] - YpMECPS + CTP + Mg<br /> | **[[3fpi]] - YpMECPS + CTP + Mg<br /> | ||
| + | **[[5b8f]] - MECPS + CMP + Mg – ''Pseudomonas aeruginosa''<br /> | ||
| + | **[[5iwy]] - BsMECPS + CMP + Mg <br /> | ||
**[[1iv2]] - TtMECPS (mutant) + CDP + Mg<br /> | **[[1iv2]] - TtMECPS (mutant) + CDP + Mg<br /> | ||
**[[1iv4]] - TtMECPS (mutant) + CMP + Mg<br /> | **[[1iv4]] - TtMECPS (mutant) + CMP + Mg<br /> | ||
Revision as of 07:37, 19 July 2017
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3D structures of MECDP synthase
Updated on 19-July-2017
References
- ↑ Richard SB, Ferrer JL, Bowman ME, Lillo AM, Tetzlaff CN, Cane DE, Noel JP. Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. J Biol Chem. 2002 Mar 8;277(10):8667-72. Epub 2002 Jan 10. PMID:11786530 doi:http://dx.doi.org/10.1074/jbc.C100739200
- ↑ Kishida H, Wada T, Unzai S, Kuzuyama T, Takagi M, Terada T, Shirouzu M, Yokoyama S, Tame JR, Park SY. Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis. Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):23-31. Epub 2002, Dec 19. PMID:12499535
- ↑ Kemp LE, Bond CS, Hunter WN. Structure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6591-6. Epub 2002 May 7. PMID:11997478 doi:10.1073/pnas.102679799
