Mitogen-activated protein kinase kinase kinase
From Proteopedia
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<StructureSection load='2o2v' size='350' side='right' caption='Mitogen-activated protein kinase kinase kinase 3 (green) complex with MAP2K5 PHOX domain (grey) (PDB code [[2o2v]]).' scene=''> | <StructureSection load='2o2v' size='350' side='right' caption='Mitogen-activated protein kinase kinase kinase 3 (green) complex with MAP2K5 PHOX domain (grey) (PDB code [[2o2v]]).' scene=''> | ||
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== Disease == | == Disease == | ||
| - | MAP3K1 mutations are observed in various cancer types and in particular in luminal beast cancer. | + | MAP3K1 mutations are observed in various cancer types and in particular in luminal beast cancer<ref>PMID:11897507</ref>. |
</StructureSection> | </StructureSection> | ||
== 3D Structures of Mitogen-activated protein kinase kinase kinase== | == 3D Structures of Mitogen-activated protein kinase kinase kinase== | ||
Revision as of 06:14, 24 July 2017
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3D Structures of Mitogen-activated protein kinase kinase kinase
Updated on 24-July-2017
References
- ↑ Ellinger-Ziegelbauer H, Brown K, Kelly K, Siebenlist U. Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative. J Biol Chem. 1997 Jan 31;272(5):2668-74. PMID:9006902
- ↑ Santen RJ, Song RX, McPherson R, Kumar R, Adam L, Jeng MH, Yue W. The role of mitogen-activated protein (MAP) kinase in breast cancer. J Steroid Biochem Mol Biol. 2002 Feb;80(2):239-56. PMID:11897507
