Muconate cycloisomerase
From Proteopedia
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| + | <StructureSection load='3fyy' size='350' side='right' caption='Muconate cycloisomerase dimer complex with Mg+2 ion (green) (PDB entry [[3fyy]])' scene=''> | ||
'''Muconate cycloisomerase''' (MCI) catalyzes the formation of muconolactone from ''cis,cis''-muconate. It is part of the B-ketoadipate pathway in the metabolism of aromatic compounds<ref>PMID:9726873</ref>. MCI breaks down lignin-derived catechol and protocatechuate. | '''Muconate cycloisomerase''' (MCI) catalyzes the formation of muconolactone from ''cis,cis''-muconate. It is part of the B-ketoadipate pathway in the metabolism of aromatic compounds<ref>PMID:9726873</ref>. MCI breaks down lignin-derived catechol and protocatechuate. | ||
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*'''3-carboxy-''cis,cis''-muconate cycloisomerase''' catalyzes the reversible conversion of 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 3-chloro-''cis,cis''-muconate<ref>PMID:5916392</ref>.<br /> | *'''3-carboxy-''cis,cis''-muconate cycloisomerase''' catalyzes the reversible conversion of 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 3-chloro-''cis,cis''-muconate<ref>PMID:5916392</ref>.<br /> | ||
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== 3D Structures of muconate cycloisomerase == | == 3D Structures of muconate cycloisomerase == | ||
Revision as of 10:32, 25 July 2017
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3D Structures of muconate cycloisomerase
Updated on 25-July-2017
References
- ↑ Vollmer MD, Hoier H, Hecht HJ, Schell U, Groning J, Goldman A, Schlomann M. Substrate specificity of and product formation by muconate cycloisomerases: an analysis of wild-type enzymes and engineered variants. Appl Environ Microbiol. 1998 Sep;64(9):3290-9. PMID:9726873
- ↑ Schmidt E, Knackmuss HJ. Chemical structure and biodegradability of halogenated aromatic compounds. Conversion of chlorinated muconic acids into maleoylacetic acid. Biochem J. 1980 Oct 15;192(1):339-47. PMID:7305906
- ↑ Ornston LN. The conversion of catechol and protocatechuate to beta-ketoadipate by Pseudomonas putida. II. Enzymes of the protocatechuate pathway. J Biol Chem. 1966 Aug 25;241(16):3787-94. PMID:5916392
