This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2vww
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | == | + | |
| + | ==ephB4 kinase domain inhibitor complex== | ||
<StructureSection load='2vww' size='340' side='right' caption='[[2vww]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='2vww' size='340' side='right' caption='[[2vww]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2vww]] is a 1 chain structure | + | <table><tr><td colspan='2'>[[2vww]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VWW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VWW FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X2:N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5-+TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE'>7X2</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X2:N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5-+TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE'>7X2</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vx0|2vx0]], [[2vwv|2vwv]], [[2vwz|2vwz]], [[2vwy|2vwy]], [[2vx1|2vx1]], [[2vwx|2vwx]], [[2vwu|2vwu]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vx0|2vx0]], [[2vwv|2vwv]], [[2vwz|2vwz]], [[2vwy|2vwy]], [[2vx1|2vx1]], [[2vwx|2vwx]], [[2vwu|2vwu]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vww OCA], [http://pdbe.org/2vww PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vww RCSB], [http://www.ebi.ac.uk/pdbsum/2vww PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vww OCA], [http://pdbe.org/2vww PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vww RCSB], [http://www.ebi.ac.uk/pdbsum/2vww PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vww ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 36: | Line 37: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Human]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Barratt, D]] | [[Category: Barratt, D]] | ||
| Line 43: | Line 43: | ||
[[Category: Kettle, J G]] | [[Category: Kettle, J G]] | ||
[[Category: Leach, A G]] | [[Category: Leach, A G]] | ||
| - | [[Category: | + | [[Category: McCall, E J]] |
[[Category: Read, J]] | [[Category: Read, J]] | ||
[[Category: Valentine, A L]] | [[Category: Valentine, A L]] | ||
| Line 53: | Line 53: | ||
[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
[[Category: Receptor tyrosine kinase]] | [[Category: Receptor tyrosine kinase]] | ||
Revision as of 08:31, 3 August 2017
ephB4 kinase domain inhibitor complex
| |||||||||||
Categories: Receptor protein-tyrosine kinase | Barratt, D | Brassington, C A | Green, I | Kettle, J G | Leach, A G | McCall, E J | Read, J | Valentine, A L | Atp-binding | Glycoprotein | Kinase | Membrane | Mutant | Nucleotide-binding | Phosphoprotein | Polymorphism | Receptor | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase | Unphosphorylated
