2vx1

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==EPHB4 KINASE DOMAIN INHIBITOR COMPLEX==
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==ephB4 kinase domain inhibitor complex==
<StructureSection load='2vx1' size='340' side='right' caption='[[2vx1]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2vx1' size='340' side='right' caption='[[2vx1]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vx1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vx1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X8:3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE'>7X8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7X8:3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE'>7X8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vwu|2vwu]], [[2vwv|2vwv]], [[2vwy|2vwy]], [[2vww|2vww]], [[2vwx|2vwx]], [[2vwz|2vwz]], [[2vx0|2vx0]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bba|2bba]], [[2vwu|2vwu]], [[2vwv|2vwv]], [[2vwy|2vwy]], [[2vww|2vww]], [[2vwx|2vwx]], [[2vwz|2vwz]], [[2vx0|2vx0]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx1 OCA], [http://pdbe.org/2vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx1 OCA], [http://pdbe.org/2vx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
 
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Barratt, D]]
[[Category: Barratt, D]]
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[[Category: Kettle, J G]]
[[Category: Kettle, J G]]
[[Category: Leach, A G]]
[[Category: Leach, A G]]
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[[Category: Mccall, E J]]
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[[Category: McCall, E J]]
[[Category: Read, J]]
[[Category: Read, J]]
[[Category: Valentine, A L]]
[[Category: Valentine, A L]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Receptor tyrosine kinase]]
[[Category: Receptor tyrosine kinase]]

Revision as of 08:40, 3 August 2017

ephB4 kinase domain inhibitor complex

2vx1, resolution 1.65Å

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