This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2c4t
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ==X- | + | |
| + | ==X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with an inhibitor, an analogue of S- adenosyl methionine== | ||
<StructureSection load='2c4t' size='340' side='right' caption='[[2c4t]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2c4t' size='340' side='right' caption='[[2c4t]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2c4t]] is a 3 chain structure | + | <table><tr><td colspan='2'>[[2c4t]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C4T FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SA8:S-5-AZAMETHIONINE-5-DEOXYADENOSINE'>SA8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SA8:S-5-AZAMETHIONINE-5-DEOXYADENOSINE'>SA8</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rqp|1rqp]], [[1rqr|1rqr]], [[2c2w|2c2w]], [[2c4u|2c4u]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rqp|1rqp]], [[1rqr|1rqr]], [[2c2w|2c2w]], [[2c4u|2c4u]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosyl-fluoride_synthase Adenosyl-fluoride synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.63 2.5.1.63] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosyl-fluoride_synthase Adenosyl-fluoride synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.63 2.5.1.63] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4t OCA], [http://pdbe.org/2c4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c4t RCSB], [http://www.ebi.ac.uk/pdbsum/2c4t PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4t OCA], [http://pdbe.org/2c4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c4t RCSB], [http://www.ebi.ac.uk/pdbsum/2c4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c4t ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
| Line 16: | Line 17: | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c4t ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Streptomyces cattleya kahan et al. 1979]] | ||
[[Category: Adenosyl-fluoride synthase]] | [[Category: Adenosyl-fluoride synthase]] | ||
[[Category: Deng, H]] | [[Category: Deng, H]] | ||
[[Category: Hagan, D O]] | [[Category: Hagan, D O]] | ||
| - | [[Category: | + | [[Category: McEwan, A R]] |
| - | [[Category: | + | [[Category: McGlinchey, R P]] |
[[Category: Naismith, J H]] | [[Category: Naismith, J H]] | ||
[[Category: Robinson, D R]] | [[Category: Robinson, D R]] | ||
Revision as of 10:49, 3 August 2017
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with an inhibitor, an analogue of S- adenosyl methionine
| |||||||||||
