Leucine transporter
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='3usg' size='350' side='right' caption='Structure of leucine transporter complex with leucine, lipid membrane fragments and Na+ | + | <StructureSection load='3usg' size='350' side='right' caption='Structure of leucine transporter complex with leucine, lipid membrane fragments and Na+ ions (purple) (PDB entry [[3usg]])' scene='56/564069/Cv/1'> |
== Function == | == Function == | ||
'''Leucine transporter''' (LeuT) is a membrane protein which is comprised of 12 transmembrane helices forming a channel. LeuT clears the synapse after signal transduction. LeuT utilizes the electrochemical potential gradient of Na+ ions across the membrane to catalyze the uptake of leucine. The LeuT is a homodimer<ref>PMID:15980244</ref>. | '''Leucine transporter''' (LeuT) is a membrane protein which is comprised of 12 transmembrane helices forming a channel. LeuT clears the synapse after signal transduction. LeuT utilizes the electrochemical potential gradient of Na+ ions across the membrane to catalyze the uptake of leucine. The LeuT is a homodimer<ref>PMID:15980244</ref>. | ||
| Line 7: | Line 7: | ||
== Structural highlights == | == Structural highlights == | ||
| - | The leucine binding pocket of LeuT contains 2 Na+ ions<ref>PMID:22245965</ref>. | + | <scene name='56/564069/Cv/2'>Leucine transporter complex with leucine, lipid membrane fragments and Na+ ions</scene>. The leucine binding pocket of LeuT contains 2 Na+ ions<ref>PMID:22245965</ref>. |
==3D structures of leucine transporter== | ==3D structures of leucine transporter== | ||
Revision as of 10:19, 8 August 2017
| |||||||||||
