1w3z
From Proteopedia
Line 4: | Line 4: | ||
|PDB= 1w3z |SIZE=350|CAPTION= <scene name='initialview01'>1w3z</scene>, resolution 3.2Å | |PDB= 1w3z |SIZE=350|CAPTION= <scene name='initialview01'>1w3z</scene>, resolution 3.2Å | ||
|SITE= | |SITE= | ||
- | |LIGAND= | + | |LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
+ | |DOMAIN= | ||
+ | |RELATEDENTRY= | ||
+ | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w3z OCA], [http://www.ebi.ac.uk/pdbsum/1w3z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1w3z RCSB]</span> | ||
}} | }} | ||
Line 40: | Line 43: | ||
[[Category: tick]] | [[Category: tick]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:30:56 2008'' |
Revision as of 21:30, 30 March 2008
| |||||||
, resolution 3.2Å | |||||||
---|---|---|---|---|---|---|---|
Ligands: | |||||||
Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
SEMET DERIVATIVE OF BBCRASP-1 FROM BORRELIA BURGDORFERI
Overview
Borrelia burgdorferi, a spirochete transmitted to human hosts during feeding of infected Ixodes ticks, is the causative agent of Lyme disease. Serum-resistant B. burgdorferi strains cause a chronic, multisystemic form of the disease and bind complement factor H (FH) and FH-like protein 1 (FHL-1) on the spirochete surface. Here we report the atomic structure for the key FHL-1- and FH-binding protein BbCRASP-1 and reveal a homodimer that presents a novel target for drug design.
About this Structure
1W3Z is a Single protein structure of sequence from Borrelia burgdorferi. Full crystallographic information is available from OCA.
Reference
A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi., Cordes FS, Roversi P, Kraiczy P, Simon MM, Brade V, Jahraus O, Wallis R, Skerka C, Zipfel PF, Wallich R, Lea SM, Nat Struct Mol Biol. 2005 Mar;12(3):276-7. Epub 2005 Feb 13. PMID:15711564
Page seeded by OCA on Mon Mar 31 00:30:56 2008
Categories: Borrelia burgdorferi | Single protein | Brade, V. | Cordes, F S. | Goodstadt, L. | Kirschfink, M. | Kraiczy, P. | Lea, S M. | Ponting, C. | Roversi, P. | Simon, M M. | Skerka, C. | Wallich, R. | Zipfel, P. | Complement regulator acquiring surface protein | Factor h binding | Lyme borreliosis | Selenomethionine | Tick