Nitroreductase
From Proteopedia
(Difference between revisions)
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**[[1f5v ]], [[1oo5]] – EcNR – ''Escherichia coli''<br /> | **[[1f5v ]], [[1oo5]] – EcNR – ''Escherichia coli''<br /> | ||
| + | **[[3x21]], [[3x22]] – EcNR (mutant)<br /> | ||
**[[3bm1]], [[1ds7]] – EcNR minimal<br /> | **[[3bm1]], [[1ds7]] – EcNR minimal<br /> | ||
**[[3bm2]] – EcNR minimal -FMN<br /> | **[[3bm2]] – EcNR minimal -FMN<br /> | ||
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**[[3ge6]] – NR – ''Exiguobacterium sibiricum''<br /> | **[[3ge6]] – NR – ''Exiguobacterium sibiricum''<br /> | ||
**[[4dn2]] – NR – ''Geobacter metallireducens''<br /> | **[[4dn2]] – NR – ''Geobacter metallireducens''<br /> | ||
| + | **[[5ko7]], [[5ko8]], [[5krd]] – NR – ''Haliscomenobacter hydrossis''<br /> | ||
*Copper-induced nitroreductase | *Copper-induced nitroreductase | ||
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*Nitroreductase binary complex | *Nitroreductase binary complex | ||
| - | **[[1kqb]] – EclNR + benzoate<br /> | + | **[[1kqb]], [[5j8g]]– EclNR + benzoate derivative<br /> |
**[[1kqc]] – EclNR + acetate<br /> | **[[1kqc]] – EclNR + acetate<br /> | ||
**[[1ylr]], [[1ylu]] - EcNR + acetate<br /> | **[[1ylr]], [[1ylu]] - EcNR + acetate<br /> | ||
| - | **[[1icr]], [[1icu]], [[1icv]] – EcNR + | + | **[[1icr]], [[1icu]], [[1icv]], [[5j8d]] – EcNR + NAD derivative<br /> |
**[[1ooq]] – EcNR + dicoumarol<br /> | **[[1ooq]] – EcNR + dicoumarol<br /> | ||
**[[1oo6]], [[1oon]], [[1idt]] – EcNR + benzamide derivative<br /> | **[[1oo6]], [[1oon]], [[1idt]] – EcNR + benzamide derivative<br /> | ||
Revision as of 10:21, 24 August 2017
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3D structures of nitroreductase
Updated on 24-August-2017
References
- ↑ Lovering AL, Hyde EI, Searle PF, White SA. The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J Mol Biol. 2001 May 25;309(1):203-13. PMID:11491290 doi:10.1006/jmbi.2001.4653
- ↑ Williams EM, Little RF, Mowday AM, Rich MH, Chan-Hyams JV, Copp JN, Smaill JB, Patterson AV, Ackerley DF. Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility. Biochem J. 2015 Oct 15;471(2):131-53. doi: 10.1042/BJ20150650. PMID:26431849 doi:http://dx.doi.org/10.1042/BJ20150650
