Nucleoporin
From Proteopedia
(Difference between revisions)
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<StructureSection load='1xip' size='350' side='right' caption='Yeast nucleoporin NUP159 N-terminal domain (PDB entry [[1xip]])' scene='Nucleoporin/Cv/1'> | <StructureSection load='1xip' size='350' side='right' caption='Yeast nucleoporin NUP159 N-terminal domain (PDB entry [[1xip]])' scene='Nucleoporin/Cv/1'> | ||
== Function == | == Function == | ||
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**[[3p3d]] - NUP53 RRM domain - ''Pischia guillermondii''<br /> | **[[3p3d]] - NUP53 RRM domain - ''Pischia guillermondii''<br /> | ||
**[[4lir]] – hNUP53 residues 151-266<br /> | **[[4lir]] – hNUP53 residues 151-266<br /> | ||
| + | **[[5hb8]], [[5hb7]] – CtNUP53 - ''Chaetomium thermophilum''<br /> | ||
| + | **[[5hb3]] – CtNUP53 + NUP NIC96 <br /> | ||
*NUP54 | *NUP54 | ||
**[[3t97]] – rNUP54 + NUP62 - rat<br /> | **[[3t97]] – rNUP54 + NUP62 - rat<br /> | ||
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**[[4jq5]] – hNUP58/45 <br /> | **[[4jq5]] – hNUP58/45 <br /> | ||
*NUP82 | *NUP82 | ||
| - | **[[3pbp]] – yNUP82 NTD + NUP116 CTD + NUP159 | + | **[[3pbp]] – yNUP82 NTD + NUP116 CTD + NUP159 CTD<br /> |
| - | **[[3tkn]] - yNUP82 NTD + NUP98 + NUP159 | + | **[[3tkn]] - yNUP82 NTD + NUP98 + NUP159 CTD<br /> |
| + | **[[5cww]] – CtNUP82 + CtNUP145 CTD peptide + Ct159 CTD peptide<br /> | ||
*NUP84 | *NUP84 | ||
**[[3jro]], [[3iko]] – yNUP84+NUP145+protein Sec13<br /> | **[[3jro]], [[3iko]] – yNUP84+NUP145+protein Sec13<br /> | ||
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**[[3kep]], [[3kes]] – yNUP145 autoproteolytic domain<br /> | **[[3kep]], [[3kes]] – yNUP145 autoproteolytic domain<br /> | ||
**[[3jrp]] - yNUP145+protein Sec13<br /> | **[[3jrp]] - yNUP145+protein Sec13<br /> | ||
| + | **[[5hb5]] – CtNUP145 <br /> | ||
| + | **[[5hb6]] – CtNUP145 (mutant)<br /> | ||
| + | *NUP152 | ||
| + | **[[5tvz]] – yNUP152 Ig-like repeats - NMR<br /> | ||
*NUP153 | *NUP153 | ||
**[[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]], [[3ch5]] – hNUP153+RAN<br /> | **[[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]], [[3ch5]] – hNUP153+RAN<br /> | ||
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*NUP170 | *NUP170 | ||
**[[3i5p]], [[3i5q]] – yNUP170<br /> | **[[3i5p]], [[3i5q]] – yNUP170<br /> | ||
| + | **[[5hb1]] – CtNUP170 <br /> | ||
| + | **[[5haz]] – CtNUP170 CTD<br /> | ||
| + | **[[5hay]] – CtNUP170 CTD (mutant)<br /> | ||
| + | **[[5hb0]] – CtNUP170 (mutant) + CtNUP145 peptide<br /> | ||
| + | **[[5hax]] – CtNUP170 NTD + CtNUP53 peptide<br /> | ||
*NUP192 | *NUP192 | ||
**[[4ifq]] – yNUP192<br /> | **[[4ifq]] – yNUP192<br /> | ||
| + | **[[5hb4]] – CtNUP192 <br /> | ||
*NUP214 | *NUP214 | ||
**[[3fmo]], [[3fmp]], [[3fhc]] – hNUP214+dead-box helicase<br /> | **[[3fmo]], [[3fmp]], [[3fhc]] – hNUP214+dead-box helicase<br /> | ||
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**[[2rfo]], [[2qx5]] – yNic96<br /> | **[[2rfo]], [[2qx5]] – yNic96<br /> | ||
| + | **[[5hb2]] – CtNic96 <br /> | ||
**[[1gyb]] – NUP+yNTF2<br /> | **[[1gyb]] – NUP+yNTF2<br /> | ||
}} | }} | ||
Revision as of 06:47, 28 August 2017
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3D Structures of Nucleoporin
Updated on 28-August-2017
References
- ↑ Doye V, Hurt E. From nucleoporins to nuclear pore complexes. Curr Opin Cell Biol. 1997 Jun;9(3):401-11. PMID:9159086
- ↑ Belanger KD, Kenna MA, Wei S, Davis LI. Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J Cell Biol. 1994 Aug;126(3):619-30. PMID:8045927
- ↑ Solsbacher J, Maurer P, Vogel F, Schlenstedt G. Nup2p, a yeast nucleoporin, functions in bidirectional transport of importin alpha. Mol Cell Biol. 2000 Nov;20(22):8468-79. PMID:11046143
- ↑ Cronshaw JM, Matunis MJ. The nuclear pore complex: disease associations and functional correlations. Trends Endocrinol Metab. 2004 Jan-Feb;15(1):34-9. PMID:14693424
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