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Nucleoprotein

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Line 23: Line 23:
**[[3pto]] - VvNP – Vesicular stomatitis Indiana virus<br />
**[[3pto]] - VvNP – Vesicular stomatitis Indiana virus<br />
**[[2qvj]] – VvNP (mutant)<br />
**[[2qvj]] – VvNP (mutant)<br />
-
**[[2k48]] – NP N terminal – Andes virus - NMR<br />
+
**[[5e04]] - AvNP – Andes virus<br />
 +
**[[2k48]] – AvNP N terminal - NMR<br />
**[[1ssk]] - ScvNP N terminal – SARS coronavirus – NMR<br />
**[[1ssk]] - ScvNP N terminal – SARS coronavirus – NMR<br />
-
**[[4j3k]] – ScvNP N terminal<br />
+
**[[4j3k]], [[5n4k]] – ScvNP N terminal<br />
 +
**[[5epw]] – ScvNP C terminal<br />
**[[2gib]] – ScvNP dimerization domain<br />
**[[2gib]] – ScvNP dimerization domain<br />
**[[2jw8]] - ScvNP dimerization domain – NMR<br />
**[[2jw8]] - ScvNP dimerization domain – NMR<br />
Line 31: Line 33:
**[[3hd4]] – NP N terminal – Murine hepatitis virus<br />
**[[3hd4]] – NP N terminal – Murine hepatitis virus<br />
**[[2wfs]], [[2ymn]] – IvNP – Cryo EM – Influenza virus<br />
**[[2wfs]], [[2ymn]] – IvNP – Cryo EM – Influenza virus<br />
-
**[[4dys]], [[4iry]] – IvNP <br />
 
**[[3zdp]], [[4dyt]] – IvNP (mutant)<br />
**[[3zdp]], [[4dyt]] – IvNP (mutant)<br />
-
**[[2q06]], [[2iqh]], [[3tj0]] – IvNP<br />
+
**[[2q06]], [[2iqh]], [[3tj0]], [[4dys]], [[4iry]], [[5b7b]] – IvNP<br />
**[[2i8b]] – EvNP C terminal – Ebola virus – NMR<br />
**[[2i8b]] – EvNP C terminal – Ebola virus – NMR<br />
-
**[[3v7o]], [[4qaz]], [[4qb0]] - EvNP C terminal<br />
+
**[[3v7o]], [[4qaz]], [[4qb0]], [[5dsd]] - EvNP C terminal<br />
 +
**[[4z9p]] - EvNP core domain<br />
 +
**[[5dvw]] - EvNP V30 residues 142-272<br />
**[[1yvr]] – XlNP Ro – ''Xenopus laevis''<br />
**[[1yvr]] – XlNP Ro – ''Xenopus laevis''<br />
**[[1wwf]] – MvNP P10 – Moloney murine leukemia virus – NMR<br />
**[[1wwf]] – MvNP P10 – Moloney murine leukemia virus – NMR<br />
Line 48: Line 51:
**[[4idu]], [[4idx]] – SvNP – Schmallenberg virus<br />
**[[4idu]], [[4idx]] – SvNP – Schmallenberg virus<br />
**[[4k7e]] – NP C terminal – Junin virus<br />
**[[4k7e]] – NP C terminal – Junin virus<br />
-
**[[4o6h]] – NP C terminal – Lymphocytic choriomeningitis virus<br />
+
**[[4o6h]], [[4o6i]] – NP C terminal – Lymphocytic choriomeningitis virus<br />
 +
**[[5ls4]], [[5lrp]] – NP exonuclease domain – Mopeia virus<br />
 +
**[[5ip1]] - TsvNP - Tomato spotted virus<br />
 +
**[[5f5m]] - LvmvNP – Lake Victoria Margvirus virus<br />
 +
**[[4xze]] - NP - Hazara virus<br />
 +
**[[4xzc]] - NP - Hupe virus<br />
 +
**[[4xza]], [[5xz8]] - NP - Erve virus<br />
 +
**[[4uce]], [[4ucd]], [[4uc7]], [[4uc6]] – RsvNP N terminal – Human respiratory syncytial virus<br />
-
*Nucleoprotein binary complex
+
*Nucleoprotein complex
**[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
**[[3mx2]], [[3mx5]] – LvNP + nucleotide<br />
Line 58: Line 68:
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />
**[[3hhw]], [[3pmk]] – VvNP + phosphoprotein<br />
**[[3hhz]] - VvNP + phosphoprotein + RNA<br />
**[[3hhz]] - VvNP + phosphoprotein + RNA<br />
 +
**[[5uk4]] - VvNP + nanobody + RNA<br />
**[[4co6]] - NP + phosphoprotein – Nipah virus<br />
**[[4co6]] - NP + phosphoprotein – Nipah virus<br />
-
**[[2wj8]], [[2yhm]], [[4bkk]] – NP + RNA – Human respiratory syncytial virus<br />
+
**[[2wj8]], [[2yhm]], [[4bkk]] – RsvNP + RNA <br />
 +
**[[4ucc]] – RsvNP N terminal + inhibitor<br />
 +
**[[4ucb]], [[4uca]] – RsvNP N terminal + phosphoprotein<br />
 +
**[[4uc9]], [[4uc8]] – RsvNP N terminal + phosphoprotein peptidebr />
**[[2i91]], [[1yvp]] – XlNP Ro + RNA <br />
**[[2i91]], [[1yvp]] – XlNP Ro + RNA <br />
**[[2gtt]] – NP + RNA – Rabies virus<br />
**[[2gtt]] – NP + RNA – Rabies virus<br />
Line 65: Line 79:
**[[3ro5]], [[4dya]], [[4dyb]], [[4dyn]], [[4dyp]], [[3tg6]] – IvNP + ligand<br />
**[[3ro5]], [[4dya]], [[4dyb]], [[4dyn]], [[4dyp]], [[3tg6]] – IvNP + ligand<br />
**[[4bbl]] – IvNP + RNA – Cryo EM<br />
**[[4bbl]] – IvNP + RNA – Cryo EM<br />
 +
**[[5tjw]] - IvNP + nanobody <br />
**[[3zla]] – BvNP + RNA – Bunyamwera virus<br />
**[[3zla]] – BvNP + RNA – Bunyamwera virus<br />
**[[4ijs]] – BvNP (mutant) + RNA <br />
**[[4ijs]] – BvNP (mutant) + RNA <br />
Line 74: Line 89:
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
**[[4lmt]] – ScvNP N terminal + quinoline derivative <br />
**[[4ypi]] - EvNP + peptide – Cryo EM<br />
**[[4ypi]] - EvNP + peptide – Cryo EM<br />
 +
**[[5vao]], [[5vap]] - EvNP VP30 + NP peptide <br />
 +
**[[5sxq]], [[5f5o]] - LvmvNP + VP35 peptide <br />
 +
**[[5ip3]] - TsvNP + DNA <br />
 +
**[[5ip2]] - TsvNP + RNA <br />
 +
**[[5fvc]] - NP + RNA – Human metapneumovirus<br />
 +
**[[4xjn]] - NP + RNA – Parainfluenza virus<br />
*'''Ribonucleoprotein'''
*'''Ribonucleoprotein'''
Line 79: Line 100:
**[[2lbw]] – yRNP subunit 2 residues 36-156 (mutant) – yeast – NMR<br />
**[[2lbw]] – yRNP subunit 2 residues 36-156 (mutant) – yeast – NMR<br />
**[[2lbx]] - yRNP subunit 2 residues 36-156 – NMR<br />
**[[2lbx]] - yRNP subunit 2 residues 36-156 – NMR<br />
-
**[[4h5l]], [[4csg]] – TvRNP – Toscana virus<br />
+
**[[4h5l]], [[4csg]], [[5fva]] – TvRNP – Toscana virus<br />
**[[4csf]] – TvRNP + RNA<br />
**[[4csf]] – TvRNP + RNA<br />
**[[4uft]] – RNP + RNA – Measles virus<br />
**[[4uft]] – RNP + RNA – Measles virus<br />

Revision as of 08:38, 28 August 2017

Nucleoprotein from Lassa virus trimer complex with TTP and Zn+2 ions (grey) 3mx2

Drag the structure with the mouse to rotate

3D Structures of Nucleoprotein

Updated on 28-August-2017

References

  1. ↑ Echols H. Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination. J Biol Chem. 1990 Sep 5;265(25):14697-700. PMID:2203758
  2. ↑ Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 2004 May;14(5):226-32. PMID:15130578 doi:http://dx.doi.org/10.1016/j.tcb.2004.03.010
  3. ↑ He Y, Smith R. Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B. Cell Mol Life Sci. 2009 Apr;66(7):1239-56. doi: 10.1007/s00018-008-8532-1. PMID:19099192 doi:http://dx.doi.org/10.1007/s00018-008-8532-1

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman

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