Obscurin

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<StructureSection load='2yz8' size='350' side='right' caption='Human obscurin of 32th IG-like domain residues 3184-3273 (PDB entry [[2yz8]])' scene=''>
<StructureSection load='2yz8' size='350' side='right' caption='Human obscurin of 32th IG-like domain residues 3184-3273 (PDB entry [[2yz8]])' scene=''>
== Function ==
== Function ==
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**[[2edq]] - hObs Ig domain residues 3713-3806 – NMR<BR />
**[[2edq]] - hObs Ig domain residues 3713-3806 – NMR<BR />
**[[2edl]] - hObs Ig domain residues 3801-3897 – NMR<BR />
**[[2edl]] - hObs Ig domain residues 3801-3897 – NMR<BR />
 +
**[[2mwc]], [[4rsv]] - hObs Ig domain residues 4337-4429 – NMR<br />
 +
**[[2n56]] - hObs Ig domain residues 4330-4524 – NMR<br />
**[[1v1c]] - hObs SH3 domain residues 5601-5668 – NMR<BR />
**[[1v1c]] - hObs SH3 domain residues 5601-5668 – NMR<BR />

Revision as of 10:08, 28 August 2017

Human obscurin of 32th IG-like domain residues 3184-3273 (PDB entry 2yz8)

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3D structures of obscurin

28-August-2017

References

  1. Kontrogianni-Konstantopoulos A, Catino DH, Strong JC, Sutter S, Borisov AB, Pumplin DW, Russell MW, Bloch RJ. Obscurin modulates the assembly and organization of sarcomeres and the sarcoplasmic reticulum. FASEB J. 2006 Oct;20(12):2102-11. PMID:17012262 doi:10.1096/fj.06-5761com
  2. Arimura T, Matsumoto Y, Okazaki O, Hayashi T, Takahashi M, Inagaki N, Hinohara K, Ashizawa N, Yano K, Kimura A. Structural analysis of obscurin gene in hypertrophic cardiomyopathy. Biochem Biophys Res Commun. 2007 Oct 19;362(2):281-7. Epub 2007 Aug 13. PMID:17716621 doi:10.1016/j.bbrc.2007.07.183

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Michal Harel, Alexander Berchansky

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