Penicillin-binding protein

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Line 21: Line 21:
**[[1qme]], [[1rp5]], [[2z2l]] – SpPBP 2X – ''Streptococcus pneumoniae''<br />
**[[1qme]], [[1rp5]], [[2z2l]] – SpPBP 2X – ''Streptococcus pneumoniae''<br />
**[[1k25]], [[1pyy]] – SpPBP 2X (mutant) <br />
**[[1k25]], [[1pyy]] – SpPBP 2X (mutant) <br />
 +
**[[5u47]] - PBP 2X – ''Streptococcus thermophilus''<br />
**[[2fff]] - SpPBP 1B<br />
**[[2fff]] - SpPBP 1B<br />
**[[2bg1]], [[2xd5]] - SpPBP 1B (mutant) <br />
**[[2bg1]], [[2xd5]] - SpPBP 1B (mutant) <br />
Line 30: Line 31:
**[[3it9]] – EcPBP 6<br />
**[[3it9]] – EcPBP 6<br />
**[[3vma]] – EcPBP 1B<br />
**[[3vma]] – EcPBP 1B<br />
-
**[[1mwr]], [[1vqq]] - SaPBP 2A (mutant) – ''Staphylococcus aureus''<br />
+
**[[1mwr]], [[1vqq]], [[4bl2]], [[4bl3]], [[4cpk]] - SaPBP 2A (mutant) – ''Staphylococcus aureus''<br />
**[[2olu]], [[3dwk]] – SaPBP 2<br />
**[[2olu]], [[3dwk]] – SaPBP 2<br />
**[[3vsk]] - SaPBP 3<br />
**[[3vsk]] - SaPBP 3<br />
Line 46: Line 47:
**[[3udf]] – AbPBP – ''Acinetobacter baumannii''<br />
**[[3udf]] – AbPBP – ''Acinetobacter baumannii''<br />
**[[3zg7]] – LmPBP 4 – ''Listeria monocytogenes''<br />
**[[3zg7]] – LmPBP 4 – ''Listeria monocytogenes''<br />
 +
**[[5dvy]], [[5e31]] – PBP 2 – ''Enterococcus faecium''<br />
*Penicillin-binding protein complex with antibiotics
*Penicillin-binding protein complex with antibiotics
Line 81: Line 83:
**[[4fsf]] – PaPBP + inhibitor<br />
**[[4fsf]] – PaPBP + inhibitor<br />
 +
**[[4cjn]] – SaPBP + quinazolinine derivative<br />
*'''D-alanyl-D-alanine carboxypeptidase'''
*'''D-alanyl-D-alanine carboxypeptidase'''
Line 86: Line 89:
**[[1w79]], [[1w8q]] – AcDDP – ''Actinomadura''<br />
**[[1w79]], [[1w8q]] – AcDDP – ''Actinomadura''<br />
**[[3pte]], [[1skf]] – StDDP – ''Streptomyces''<br />
**[[3pte]], [[1skf]] – StDDP – ''Streptomyces''<br />
 +
**[[4rye]] – MtDDP <br />
 +
**[[5fsr]] – EcDDP <br />
**[[1es2]], [[1es3]], [[1es4]], [[1es5]], [[1esi]], [[1j9m]] – StDDP (mutant) <br />
**[[1es2]], [[1es3]], [[1es4]], [[1es5]], [[1esi]], [[1j9m]] – StDDP (mutant) <br />
**[[1lbu]] – DDP + Zn – ''Streptomyces albus''<br />
**[[1lbu]] – DDP + Zn – ''Streptomyces albus''<br />
Line 96: Line 101:
**[[1yqs]] - StDDP + sultam inhibitor<br />
**[[1yqs]] - StDDP + sultam inhibitor<br />
**[[3zcz]] – AcDDP + inhibitor<br />
**[[3zcz]] – AcDDP + inhibitor<br />
 +
**[[5j8x]] – EcDDP + inhibitor<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:31, 30 August 2017

E. coli PBP 4 complex with the antibiotic ampicillin and glycerol 2ex6

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3D structures of penicillin-binding protein

Updated on 30-August-2017

References

  1. Spratt BG. Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc Natl Acad Sci U S A. 1975 Aug;72(8):2999-3003. PMID:1103132
  2. Beadle BM, Nicholas RA, Shoichet BK. Interaction energies between beta-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation. Protein Sci. 2001 Jun;10(6):1254-9. PMID:11369864 doi:http://dx.doi.org/10.1110/ps.52001
  3. Kishida H, Unzai S, Roper DI, Lloyd A, Park SY, Tame JR. Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics. Biochemistry. 2006 Jan 24;45(3):783-92. PMID:16411754 doi:10.1021/bi051533t

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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