5xfs
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of PE8-PPE15 in complex with EspG5 from M. tuberculosis== | |
| - | + | <StructureSection load='5xfs' size='340' side='right' caption='[[5xfs]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xfs]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XFS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xfs OCA], [http://pdbe.org/5xfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xfs RCSB], [http://www.ebi.ac.uk/pdbsum/5xfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xfs ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ESPG5_MYCTU ESPG5_MYCTU]] Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers.<ref>PMID:25155747</ref> [[http://www.uniprot.org/uniprot/PPE15_MYCTU PPE15_MYCTU]] May play a critical role in the homeostasis of triacylglycerol-containing lipid droplets in M.tuberculosis and influence the entry of the pathogen into a dormant state.<ref>PMID:27325376</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Au, S W.N]] | ||
| + | [[Category: Chen, X]] | ||
| + | [[Category: Bacterial pathogenesis]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Protein secretion]] | ||
| + | [[Category: Protein structure]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Tuberculosis]] | ||
Revision as of 14:38, 5 September 2017
Crystal structure of PE8-PPE15 in complex with EspG5 from M. tuberculosis
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