Phosphotriesterase

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Line 21: Line 21:
*Phosphotriesterase complex with metal ion
*Phosphotriesterase complex with metal ion
-
**[[1hzy]], [[4pbe]], [[4pbf]], [[4pcn]], [[4pcp]] - BdPTE + Zn<br />
+
**[[1hzy]], [[4pbe]], [[4pbf]], [[4pcn]], [[4pcp]], [[4xaf]], [[4xag]], [[4xay]], [[4xaz]], [[4xd3]], [[4xd4]], [[4xd5]], [[4xd6]] - BdPTE + Zn<br />
**[[2ob3]], [[2o4m]], [[2o4q]], [[2oql]] - BdPTE (mutant) + Zn<br />
**[[2ob3]], [[2o4m]], [[2o4q]], [[2oql]] - BdPTE (mutant) + Zn<br />
**[[3cs2]], [[3upm]], [[3ur2]], [[3ur5]], [[3ura]], [[3urb]], [[3urn]] - BdPTE (mutant) + Co<br />
**[[3cs2]], [[3upm]], [[3ur2]], [[3ur5]], [[3ura]], [[3urb]], [[3urn]] - BdPTE (mutant) + Co<br />
Line 36: Line 36:
**[[3gtf]], [[3gth]], [[3gti]], [[3gtx]], [[3gu1]], [[3gu2]], [[3gu9]] - DrPTE (mutant) + Co<br />
**[[3gtf]], [[3gth]], [[3gti]], [[3gtx]], [[3gu1]], [[3gu2]], [[3gu9]] - DrPTE (mutant) + Co<br />
**[[3htw]] - DrPTE + Mg + Co<br />
**[[3htw]] - DrPTE + Mg + Co<br />
-
**[[3orw]], [[3tn3]] - GkPTE + Co – ''Geobacillus kaustophilus''<br />
+
**[[3orw]], [[3tn3]], [[4wvx]] - GkPTE + Co – ''Geobacillus kaustophilus''<br />
-
**[[3tn4]], [[3tn5]], [[3tn6]], [[3tnb]] - GkPTE (mutant) + Co<br />
+
**[[3tn4]], [[3tn5]], [[3tn6]], [[3tnb]], [[5ch9]] - GkPTE (mutant) + Co<br />
**[[4h9u]] - GkPTE + Fe + Zn<br />
**[[4h9u]] - GkPTE + Fe + Zn<br />
**[[4h9v]], [[4h9y]], [[4ha0]] - GkPTE (mutant) + Fe + Zn<br />
**[[4h9v]], [[4h9y]], [[4ha0]] - GkPTE (mutant) + Fe + Zn<br />
Line 66: Line 66:
**[[4kf1]] - SsPTE (mutant) + Co + Fe + thiophenium derivative<br />
**[[4kf1]] - SsPTE (mutant) + Co + Fe + thiophenium derivative<br />
**[[4np7]] - AtPTE (mutant) + Co + Fe + thiophosphate<br />
**[[4np7]] - AtPTE (mutant) + Co + Fe + thiophosphate<br />
 +
**[[5vej]] - PTE + Co + F – ''Rhizobium radiobacter''<br />
}}
}}

Revision as of 09:40, 7 September 2017

Phosphotriesterase dimer complex with reaction product ethyl phosphate and Co+2 ion (pink), 3cak

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3D structures of phosphotriesterase

Updated on 07-September-2017

References

  1. Roodveldt C, Tawfik DS. Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state. Protein Eng Des Sel. 2005 Jan;18(1):51-8. PMID:15790580 doi:http://dx.doi.org/10.1093/protein/gzi005
  2. Bigley AN, Mabanglo MF, Harvey SP, Raushel FM. Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR. Biochemistry. 2015 Aug 25. PMID:26274608 doi:http://dx.doi.org/10.1021/acs.biochem.5b00629
  3. Kim J, Tsai PC, Chen SL, Himo F, Almo SC, Raushel FM. Structure of diethyl phosphate bound to the binuclear metal center of phosphotriesterase. Biochemistry. 2008 Sep 9;47(36):9497-504. Epub 2008 Aug 15. PMID:18702530 doi:10.1021/bi800971v

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky

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