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5kqj

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'''Unreleased structure'''
 
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The entry 5kqj is ON HOLD until Paper Publication
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==Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics==
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<StructureSection load='5kqj' size='340' side='right' caption='[[5kqj]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
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Authors: Bacot-Davis, V.R., Berghuis, A.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5kqj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KQJ FirstGlance]. <br>
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Description: Solution Structure of Antibiotic-Resistance Factor ANT(2'')-Ia Reveals Substrate-Regulated Conformation Dynamics
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kqj OCA], [http://pdbe.org/5kqj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kqj RCSB], [http://www.ebi.ac.uk/pdbsum/5kqj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kqj ProSAT]</span></td></tr>
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[[Category: Bacot-Davis, V.R]]
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</table>
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[[Category: Berghuis, A.M]]
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== Function ==
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[[http://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN]] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.
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__TOC__
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</StructureSection>
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[[Category: Transferase]]
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[[Category: Bacot-Davis, V R]]
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[[Category: Berghuis, A M]]
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[[Category: Aminoglycoside]]
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[[Category: Antibiotic resistance]]

Revision as of 10:13, 10 September 2017

Solution Structure of Antibiotic-Resistance Factor ANT(2)-Ia Reveals Substrate-Regulated Conformation Dynamics

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