5ijt
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Peroxiredoxin 2 Oxidized (SS)== | |
| - | + | <StructureSection load='5ijt' size='340' side='right' caption='[[5ijt]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ijt]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IJT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IJT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ijt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ijt OCA], [http://pdbe.org/5ijt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ijt RCSB], [http://www.ebi.ac.uk/pdbsum/5ijt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ijt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRDX2_HUMAN PRDX2_HUMAN]] Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Peroxiredoxin]] | ||
| + | [[Category: Bolduc, J A]] | ||
| + | [[Category: Haynes, A C]] | ||
| + | [[Category: Lowther, W T]] | ||
| + | [[Category: Decamer disulfide bond]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 09:30, 13 September 2017
Human Peroxiredoxin 2 Oxidized (SS)
| |||||||||||
