This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5arg
From Proteopedia
| Line 1: | Line 1: | ||
| - | ==SMYD2 in complex with SGC probe | + | ==SMYD2 in complex with SGC probe BAY-598== |
<StructureSection load='5arg' size='340' side='right' caption='[[5arg]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='5arg' size='340' side='right' caption='[[5arg]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5arg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ARG FirstGlance]. <br> | <table><tr><td colspan='2'>[[5arg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ARG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ARG FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=H41:N-[1-(N-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL)-3-(3,4-DICHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE'>H41</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=H41:N-[1-(N-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL)-3-(3,4-DICHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE'>H41</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5arg OCA], [http://pdbe.org/5arg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5arg RCSB], [http://www.ebi.ac.uk/pdbsum/5arg PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5arg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5arg OCA], [http://pdbe.org/5arg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5arg RCSB], [http://www.ebi.ac.uk/pdbsum/5arg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5arg ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 18: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 5arg" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5arg" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Histone methyltransferase|Histone methyltransferase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 10:27, 13 September 2017
SMYD2 in complex with SGC probe BAY-598
| |||||||||||
Categories: Badock, V | Barak, N | Brumby, T | Christ, C D | Eggert, E | Fernandez-Montalvan, A E | Hartung, I V | Hillig, R C | Koehr, S | Laak, A ter | Mowat, J | Mueller, T | Stellfeld, T | Stoeckigt, D | Stresemann, C | Weinmann, H | Weiske, J | Drug target | Methyltransferase | Oxidoreductase | Set domain | Sgc probe | Small molecule inhibitor | Transferase
