This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.

5hmj

From Proteopedia

(Difference between revisions)

Jump to: navigation, search

Revision as of 10:42, 13 September 2017

Re-refinement of 4xan: hen lysozyme with carboplatin in sodium bromide solution

Structural highlights

5hmj is a 1 chain structure with sequence from Gallus gallus. This structure supersedes the now removed PDB entries 4xan and 4nsf. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , ,
Related:	4xan
Activity:	Lysozyme, with EC number 3.2.1.17
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.^[1]

Publication Abstract from PubMed

A re-refinement of 4xan, hen egg-white lysozyme (HEWL) with carboplatin crystallized in NaBr solution, has been made and is published here as an addendum to Tanley et al. [(2014), Acta Cryst. F70, 1135-1142]. This follows a previous re-refinement and PDB deposition (4yem) by Shabalin et al. [(2015), Acta Cryst. D71, 1965-1979]. The critical evaluation of the original PDB deposition (4xan), and the subsequent critical examination of the re-refined structure (4yem), has led to an improved model (PDB code 5hmj).

Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution.,Tanley SW, Schreurs AM, Kroon-Batenburg LM, Helliwell JR Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):251-252. Epub 2016 Feb, 19. PMID:26919531^[2]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021
↑ Tanley SW, Schreurs AM, Kroon-Batenburg LM, Helliwell JR. Re-refinement of 4xan: hen egg-white lysozyme with carboplatin in sodium bromide solution. Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):251-252. Epub 2016 Feb, 19. PMID:26919531 doi:http://dx.doi.org/10.1107/S2053230X16000777

1 Structural highlights
2 Function
3 Publication Abstract from PubMed
4 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5hmj"

@@ Line 7: / Line 7: @@
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xan|4xan]]</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmj OCA], [http://pdbe.org/5hmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmj RCSB], [http://www.ebi.ac.uk/pdbsum/5hmj PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hmj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hmj OCA], [http://pdbe.org/5hmj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hmj RCSB], [http://www.ebi.ac.uk/pdbsum/5hmj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hmj ProSAT]</span></td></tr>
 </table>
 == Function ==

5hmj

From Proteopedia

Revision as of 10:42, 13 September 2017

Re-refinement of 4xan: hen lysozyme with carboplatin in sodium bromide solution

Structural highlights

Function

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

Personal tools

Navigation

Search

Toolbox