This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1h3c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
 +
==Structures of human oxidosqualene cyclase inhibitors bound to a homolgous enzyme==
==Structures of human oxidosqualene cyclase inhibitors bound to a homolgous enzyme==
<StructureSection load='1h3c' size='340' side='right' caption='[[1h3c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='1h3c' size='340' side='right' caption='[[1h3c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1h3c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27009 Atcc 27009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H3C FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1h3c]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H3C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=R79:N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>R79</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene>, <scene name='pdbligand=R79:N-(6-{[3-(4-BROMOPHENYL)-1,2-BENZISOTHIAZOL-6-YL]OXY}HEXYL)-N-METHYLPROP-2-EN-1-AMINE'>R79</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gsz|1gsz]], [[1h35|1h35]], [[1h36|1h36]], [[1h37|1h37]], [[1h39|1h39]], [[1h3a|1h3a]], [[1h3b|1h3b]], [[1sqc|1sqc]], [[2sqc|2sqc]], [[3sqc|3sqc]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gsz|1gsz]], [[1h35|1h35]], [[1h36|1h36]], [[1h37|1h37]], [[1h39|1h39]], [[1h3a|1h3a]], [[1h3b|1h3b]], [[1sqc|1sqc]], [[2sqc|2sqc]], [[3sqc|3sqc]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene--hopene_cyclase Squalene--hopene cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.17 5.4.99.17] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene--hopene_cyclase Squalene--hopene cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.17 5.4.99.17] </span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h3c OCA], [http://pdbe.org/1h3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h3c RCSB], [http://www.ebi.ac.uk/pdbsum/1h3c PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h3c OCA], [http://pdbe.org/1h3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h3c RCSB], [http://www.ebi.ac.uk/pdbsum/1h3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h3c ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
Line 16: Line 17:
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h3c ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 34: Line 35:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 27009]]
 
[[Category: Squalene--hopene cyclase]]
[[Category: Squalene--hopene cyclase]]
[[Category: Aebi, J D]]
[[Category: Aebi, J D]]

Revision as of 04:34, 21 September 2017

Structures of human oxidosqualene cyclase inhibitors bound to a homolgous enzyme

1h3c, resolution 2.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1h3c"
Personal tools