1xy2

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|PDB= 1xy2 |SIZE=350|CAPTION= <scene name='initialview01'>1xy2</scene>, resolution 1.20&Aring;
|PDB= 1xy2 |SIZE=350|CAPTION= <scene name='initialview01'>1xy2</scene>, resolution 1.20&Aring;
|SITE=
|SITE=
-
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
+
|LIGAND= <scene name='pdbligand=MPR:2-MERCAPTO-PROPION+ALDEHYDE'>MPR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xy2 OCA], [http://www.ebi.ac.uk/pdbsum/1xy2 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xy2 RCSB]</span>
}}
}}
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[[Category: Tickle, I J.]]
[[Category: Tickle, I J.]]
[[Category: Wood, S P.]]
[[Category: Wood, S P.]]
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[[Category: NH2]]
 
[[Category: hormone]]
[[Category: hormone]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:15:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:56:14 2008''

Revision as of 21:56, 30 March 2008


PDB ID 1xy2

Drag the structure with the mouse to rotate
, resolution 1.20Å
Ligands: ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING


Overview

Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation.

About this Structure

1XY2 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding., Wood SP, Tickle IJ, Treharne AM, Pitts JE, Mascarenhas Y, Li JY, Husain J, Cooper S, Blundell TL, Hruby VJ, et al., Science. 1986 May 2;232(4750):633-6. PMID:3008332

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