Journal:FEBS Open Bio:2
From Proteopedia
(Difference between revisions)

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*'''IV''' <scene name='76/763766/Cv1/19'>Complex with Quercetin 4</scene>, ligand was found only at the '''L2''' site, [[5a4v]]; | *'''IV''' <scene name='76/763766/Cv1/19'>Complex with Quercetin 4</scene>, ligand was found only at the '''L2''' site, [[5a4v]]; | ||
*'''V''' <scene name='76/763766/Cv1/20'>Complex with two molecules of S-hexyl glutathione</scene> ‘GSX’, showing the '''GSH conjugation site''', [[1gnw]]. | *'''V''' <scene name='76/763766/Cv1/20'>Complex with two molecules of S-hexyl glutathione</scene> ‘GSX’, showing the '''GSH conjugation site''', [[1gnw]]. | ||
- | *<scene name='76/763766/Cv1/22'>Click here to see summary animation how different ligands bind L1 and L2 sites</scene>. | + | *<scene name='76/763766/Cv1/22'>Click here to see summary animation how different ligands bind in L1 and L2 sites</scene>. |
'''Please pause animation before continuation:''' | '''Please pause animation before continuation:''' | ||
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*<scene name='76/763766/Cv1/25'>In complex with quercetrin 3, rotated 180°, and revealing ligand-binding site L2</scene> ([[5a4w]]). | *<scene name='76/763766/Cv1/25'>In complex with quercetrin 3, rotated 180°, and revealing ligand-binding site L2</scene> ([[5a4w]]). | ||
- | Binding | + | Binding in the L1 site: |
- | *<scene name='76/763766/Cv2/ | + | *<scene name='76/763766/Cv2/14'>Indole-3-aldehyde 1</scene>. |
+ | *<scene name='76/763766/Cv2/15'>Camalexin 2</scene>. | ||
+ | *<scene name='76/763766/Cv2/16'>Quercetrin 3</scene>. | ||
+ | *<scene name='76/763766/Cv2/17'>Click here to see summary animation how different ligands bind in the L1 site</scene>. | ||
</StructureSection> | </StructureSection> |
Revision as of 12:32, 28 September 2017
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- ↑ Ahmad L, Rylott EL, Bruce NC, Edwards R, Grogan G. Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands. FEBS Open Bio. 2016 Dec 22;7(2):122-132. doi: 10.1002/2211-5463.12168., eCollection 2017 Feb. PMID:28174680 doi:http://dx.doi.org/10.1002/2211-5463.12168
- ↑ Reinemer P, Prade L, Hof P, Neuefeind T, Huber R, Zettl R, Palme K, Schell J, Koelln I, Bartunik HD, Bieseler B. Three-dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 A resolution: structural characterization of herbicide-conjugating plant glutathione S-transferases and a novel active site architecture. J Mol Biol. 1996 Jan 19;255(2):289-309. PMID:8551521 doi:http://dx.doi.org/10.1006/jmbi.1996.0024
- ↑ Dixon DP, Sellars JD, Edwards R. The Arabidopsis phi class glutathione transferase AtGSTF2: binding and regulation by biologically active heterocyclic ligands. Biochem J. 2011 Aug 15;438(1):63-70. doi: 10.1042/BJ20101884. PMID:21631432 doi:http://dx.doi.org/10.1042/BJ20101884
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