Ribosomal protein P1

Ribosomal protein P1 (RPLP1) is one of the 3 phosphoproteins in the large 60S subunit of the eukaryotic ribosome. RPLP1 plays an important role in the elongation step of protein synthesis. RPLP1 makes a heterodimer with dimers of RPLP2^[1].

3D Structures of ribosomal protein P1

Updated on 28-September-2017

P1 in the 50S subunit

3a1y – RPLP1 N-terminal + RPLP0 N-terminal – Pyrococcus horikoshii

P1 in the 60S subunit

2lbf – hRPLP1 + RPLP2 dimerization domain – human – NMR
4beh – hRPLP1 + RPLP2 – NMR

References

1. ↑ Remacha M, Jimenez-Diaz A, Santos C, Briones E, Zambrano R, Rodriguez Gabriel MA, Guarinos E, Ballesta JP. Proteins P1, P2, and P0, components of the eukaryotic ribosome stalk. New structural and functional aspects. Biochem Cell Biol. 1995 Nov-Dec;73(11-12):959-68. PMID:8722011