Ribosome inactivating protein

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Line 36: Line 36:
**[[2g5x]] – RIP – scarlet lychnis<br />
**[[2g5x]] – RIP – scarlet lychnis<br />
**[[3ctk]] – RIP – bougainvillea<br />
**[[3ctk]] – RIP – bougainvillea<br />
-
**[[3mrw]], [[3s9q]], [[4kmk]], [[4kwn]], [[4l66]] – bgRIP – bitter gourd<br />
+
**[[3mrw]], [[3s9q]], [[4kmk]], [[4kwn]], [[4l66]], [[1cf5]], [[5gmv]], [[4rzj]] – bgRIP – bitter gourd<br />
 +
**[[1f8q]], [[1aha]], [[1ahb]], [[1ahc]], [[1mri]] – bpα-RIP – balsam pear <br />
*Type 1 ribosome inactivating protein complex with nucleotide
*Type 1 ribosome inactivating protein complex with nucleotide
**[[3mry]] – bgRIP + aminopurine<br />
**[[3mry]] – bgRIP + aminopurine<br />
-
**[[4kpv]] – bgRIP + pyrimidine derivative<br />
+
**[[4kpv]], [[5y48]] – bgRIP + pyrimidine derivative<br />
**[[3rl9]], [[3u6z]], [[3u70]], [[3v2k]] – bgRIP + adenine<br />
**[[3rl9]], [[3u6z]], [[3u70]], [[3v2k]] – bgRIP + adenine<br />
**[[4dwm]], [[4rzj]] – bgRIP + NAG<br />
**[[4dwm]], [[4rzj]] – bgRIP + NAG<br />
Line 48: Line 49:
**[[5ilx]], [[4o0o]] – bgRIP + uracil derivative<br />
**[[5ilx]], [[4o0o]] – bgRIP + uracil derivative<br />
**[[5cso]], [[5cst]] – bgRIP + cytidine<br />
**[[5cso]], [[5cst]] – bgRIP + cytidine<br />
-
**[[4kjh]], [[4zt8]] – bgRIP + cytosine<br />
+
**[[4kjh]] – bgRIP + cytosine<br />
-
**[[4zu0]] – bgRIP + CMP<br />
+
**[[4zt8]] – bgα-RIP + pyrimidine derivative + cytosine <br />
-
**[[4z44]] – bgRIP + CDP<br />
+
**[[4zu0]], [[4zz6]], [[4z44]], [[4o4q]], [[4o8e]], [[4q9f]], [[1mrg]], [[3q4p]], [[3qji]], [[4emf]], [[4emr]], [[5cso]], [[5cst]], [[5ilw]], [[5ilx]] – bgα-RIP + nucleotide <br />
-
**[[4zz6]] – bgRIP + CTP<br />
+
-
**[[4o4q]] – bgRIP + UDP<br />
+
-
**[[4o8e]] – bgRIP + UTP<br />
+
-
**[[4q9f]] – bgRIP + GMP<br />
+
-
**[[3q4p]], [[3qji]], [[4emf]], [[4emr]] – bgRIP + guanosine derivative<br />
+
*Type 1 ribosome inactivating protein complex with peptide
*Type 1 ribosome inactivating protein complex with peptide
Line 66: Line 62:
**[[3n31]], [[3n5d]], [[3n31]], [[3nfm]], [[3njs]], [[3nx9]], [[3n1d]] – baRIP + sugar <br />
**[[3n31]], [[3n5d]], [[3n31]], [[3nfm]], [[3njs]], [[3nx9]], [[3n1d]] – baRIP + sugar <br />
-
**[[3v14]], [[4fz9]], [[4guw]], [[4hoa]] – bgRIP + sugar <br />
+
**[[3v14]], [[4fz9]], [[4guw]], [[4hoa]], [[5wv1]] – bgRIP + sugar <br />
**[[4lro]] – bgRIP + spermidine<br />
**[[4lro]] – bgRIP + spermidine<br />
**[[3sj6]] – bgRIP + oxalane derivative<br />
**[[3sj6]] – bgRIP + oxalane derivative<br />
Line 74: Line 70:
**[[4jtp]] – bgRIP + ascorbic acid<br />
**[[4jtp]] – bgRIP + ascorbic acid<br />
**[[4k2z]] – bgRIP + methylethylamine<br />
**[[4k2z]] – bgRIP + methylethylamine<br />
-
**[[4kl4]] – bgRIP + PEG<br />
+
**[[5cix]] – bgRIP + triethanolamine<br />
 +
**[[5gz7]] – bgRIP + PEG<br />
 +
**[[4k2z]] – bgRIP + ethanediol<br />
**[[4jtb]] – bgRIP + phosphate<br />
**[[4jtb]] – bgRIP + phosphate<br />
**[[4lwx]] – bgRIP + peptidoglycan<br />
**[[4lwx]] – bgRIP + peptidoglycan<br />
**[[4yp2]] – bgRIP + nicotinamide<br />
**[[4yp2]] – bgRIP + nicotinamide<br />
 +
**[[1mrh]] – bpα-RIP + formycin<br />
 +
**[[4fz9]], [[4xy7]] – bgα-RIP + disaccharide <br />
 +
**[[4zt8]] – bgα-RIP + pyrimidine derivative + cytosine <br />
 +
**[[5cf9]] – bgα-RIP + NADP <br />
 +
 +
 +
 +
 +
 +
 +
 +
 +
-
*Momorcharin
 
-
**[[1f8q]], [[1aha]], [[1ahb]], [[1ahc]], [[1mri]] – bpα-RIP – balsam pear <br />
 
-
**[[1mrg]] – bpα-RIP + adenosine <br />
 
-
**[[1mrh]] – bpα-RIP + formycin<br />
 
-
**[[1cf5]] – bpβ-RIP <br />
 

Revision as of 21:18, 28 September 2017

Ribosome inactivating protein from pokeweed complex with adenine (PDB code 1qci)

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3D Structures of ribosome inactivating protein

Updated on 28-September-2017

References

  1. Stirpe F, Barbieri L. Ribosome-inactivating proteins up to date. FEBS Lett. 1986 Jan 20;195(1-2):1-8. PMID:3510899
  2. Wang S, Zheng Y, Yan J, Zhu Z, Wu Z, Ding Y. Alpha-momorcharin: a ribosome-inactivating protein from Momordica charantia, possessing DNA cleavage properties. Protein Pept Lett. 2013 Nov;20(11):1257-63. PMID:23777339
  3. Ng TB, Liu WK, Sze SF, Yeung HW. Action of alpha-momorcharin, a ribosome inactivating protein, on cultured tumor cell lines. Gen Pharmacol. 1994 Jan;25(1):75-7. PMID:8026716
  4. Kurinov IV, Myers DE, Irvin JD, Uckun FM. X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs. Protein Sci. 1999 Sep;8(9):1765-72. PMID:10493577

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