Ribosomal protein S3
From Proteopedia
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| - | <StructureSection load='1wh9' size='350' side='right' scene='' caption=' | + | <StructureSection load='1wh9' size='350' side='right' scene='' caption='Human ribosomal protein S3 KH domain (PDB code [[1wh9]])'> |
== Function == | == Function == | ||
'''Ribosomal protein S3''' (RPS3) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S3/Cv/6'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. The eukaryote 40S small subunit contains 30 proteins. It is known to be involved in the binding of initiator tRNA fMet<ref>PMID:19656744</ref>. | '''Ribosomal protein S3''' (RPS3) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S3/Cv/6'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. The eukaryote 40S small subunit contains 30 proteins. It is known to be involved in the binding of initiator tRNA fMet<ref>PMID:19656744</ref>. | ||
Current revision
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3D Structures of ribosomal protein S3
Updated on 29-September-2017
1wh9 – RPS3 KH domain – human
4bsz – RPS3 + Yar1 – yeast
References
- ↑ Yadavilli S, Mayo LD, Higgins M, Lain S, Hegde V, Deutsch WA. Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain. DNA Repair (Amst). 2009 Oct 2;8(10):1215-24. doi: 10.1016/j.dnarep.2009.07.003., Epub 2009 Aug 4. PMID:19656744 doi:http://dx.doi.org/10.1016/j.dnarep.2009.07.003
- ↑ Kim Y, Kim HD, Youn B, Park YG, Kim J. Ribosomal protein S3 is secreted as a homodimer in cancer cells. Biochem Biophys Res Commun. 2013 Nov 29;441(4):805-8. doi:, 10.1016/j.bbrc.2013.10.132. Epub 2013 Nov 5. PMID:24211576 doi:http://dx.doi.org/10.1016/j.bbrc.2013.10.132
- ↑ Ahn EH, Kim DW, Shin MJ, Kim YN, Kim HR, Woo SJ, Kim SM, Kim DS, Kim J, Park J, Eum WS, Hwang HS, Choi SY. PEP-1-ribosomal protein S3 protects dopaminergic neurons in an MPTP-induced Parkinson's disease mouse model. Free Radic Biol Med. 2013 Feb;55:36-45. doi: 10.1016/j.freeradbiomed.2012.11.008., Epub 2012 Nov 23. PMID:23178948 doi:http://dx.doi.org/10.1016/j.freeradbiomed.2012.11.008
