Ryanodine receptor
From Proteopedia
(Difference between revisions)
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**[[4i0y]], [[4i1e]], [[4i2s]], [[4i37]], [[4i3n]], [[4i6i]], [[4i8m]] – rRyR1 N terminal residues 1-559 (mutant)<br /> | **[[4i0y]], [[4i1e]], [[4i2s]], [[4i37]], [[4i3n]], [[4i6i]], [[4i8m]] – rRyR1 N terminal residues 1-559 (mutant)<br /> | ||
**[[4i96]] – rRyR1 N terminal residues 217-536 <br /> | **[[4i96]] – rRyR1 N terminal residues 217-536 <br /> | ||
| + | **[[5c33]] – rRyR1 SPRY1 domain residues 650-844 <br /> | ||
| + | **[[5c30]] – rRyR1 repeat 12 domain residues 857-1054 <br /> | ||
**[[4p9j]] – rRyR1 SPRY2 domain residues 1070-1246 <br /> | **[[4p9j]] – rRyR1 SPRY2 domain residues 1070-1246 <br /> | ||
**[[3rqr]] – rRyR1 phosphorylation domain residues 2733-2940 + tetrapeptide<br /> | **[[3rqr]] – rRyR1 phosphorylation domain residues 2733-2940 + tetrapeptide<br /> | ||
**[[4ert]] – rRyR1 phosphorylation domain residues 2733-2940 <br /> | **[[4ert]] – rRyR1 phosphorylation domain residues 2733-2940 <br /> | ||
**[[4esu]], [[4ett]], [[4etu]] – rRyR1 phosphorylation domain residues 2733-2940 (mutant)<br /> | **[[4esu]], [[4ett]], [[4etu]] – rRyR1 phosphorylation domain residues 2733-2940 (mutant)<br /> | ||
| - | **[[4uwa]], [[4uwe]] – rRyR1 – Cryo EM <br /> | + | **[[4uwa]], [[4uwe]], [[5j8v]] – rRyR1 – Cryo EM <br /> |
| - | **[[5tb0]] – rRyR1 + FKBP1B – Cryo EM <br /> | + | **[[5tb0]], [[5taw]], [[5tax]], [[5tay]], [[5taz]], [[5t15]], [[5t9m]], [[5t9n]], [[5t9r]], [[5t9s]], [[5t9v]], [[5tb0]], [[5tb1]], [[5tb2]], [[5tb3]], [[5tb4]], [[5gky]], [[5gkz]], [[5gl0]], [[5gl1]] – rRyR1 + FKBP1B – Cryo EM <br /> |
| - | **[[3j8h]] – rRyR1 + FKBP12 – EM <br /> | + | **[[5ta3]], [[5tal]], [[5tam]], [[5tan]], [[5tap]], [[5taq]], [[5tas]], [[5tat]], [[5tau]], [[5tav]] – rRyR1 + FKBP1B + caffeine + ATP – Cryo EM <br /> |
| + | **[[3j8h]] – rRyR1 + FKBP12 – Cryo EM <br /> | ||
*Ryanodine receptor 2 (Cardiac Ca+2 release channel) | *Ryanodine receptor 2 (Cardiac Ca+2 release channel) | ||
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**[[4p9l]] – mRyR2 SPRY2 domain residues 1080-1253 (mutant)<br /> | **[[4p9l]] – mRyR2 SPRY2 domain residues 1080-1253 (mutant)<br /> | ||
**[[4jkq]] – hRyR2 N terminal residues 1-606 - human <br /> | **[[4jkq]] – hRyR2 N terminal residues 1-606 - human <br /> | ||
| + | **[[5go9]], [[5goa]] – RyR2 – pig - Cryo EM <br /> | ||
| + | **[[5l1d]] – rRyR2 + FKBP12 – Cryo EM <br /> | ||
*Ryanodine receptor 3 | *Ryanodine receptor 3 | ||
Revision as of 19:07, 2 October 2017
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3D Structures of ryanodine receptor
Updated on 02-October-2017
References
- ↑ Fill M, Copello JA. Ryanodine receptor calcium release channels. Physiol Rev. 2002 Oct;82(4):893-922. PMID:12270947 doi:http://dx.doi.org/10.1152/physrev.00013.2002
- ↑ Sato K, Roesl C, Pollock N, Stowell KM. Skeletal muscle ryanodine receptor mutations associated with malignant hyperthermia showed enhanced intensity and sensitivity to triggering drugs when expressed in human embryonic kidney cells. Anesthesiology. 2013 Jul;119(1):111-8. doi: 10.1097/ALN.0b013e31828cebfe. PMID:23459219 doi:http://dx.doi.org/10.1097/ALN.0b013e31828cebfe
- ↑ McCarthy TV, Quane KA, Lynch PJ. Ryanodine receptor mutations in malignant hyperthermia and central core disease. Hum Mutat. 2000;15(5):410-7. PMID:10790202 doi:<410::AID-HUMU2>3.0.CO;2-D http://dx.doi.org/10.1002/(SICI)1098-1004(200005)15:5<410::AID-HUMU2>3.0.CO;2-D
- ↑ Tung CC, Lobo PA, Kimlicka L, Van Petegem F. The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule. Nature. 2010 Nov 3. PMID:21048710 doi:10.1038/nature09471
