Spectrin
From Proteopedia
(Difference between revisions)
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<StructureSection load='3lbx' size='340' side='right' caption='Human spectrin α (grey) and β1 chain (green) [[3lbx]]' scene=''> | <StructureSection load='3lbx' size='340' side='right' caption='Human spectrin α (grey) and β1 chain (green) [[3lbx]]' scene=''> | ||
== Function == | == Function == | ||
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**[[3f31]] – hSPTA2 tetramerization domain<br /> | **[[3f31]] – hSPTA2 tetramerization domain<br /> | ||
| + | **[[5fw9]], [[5fwb]], [[5fwc]], [[5ihi]], [[5ihk]], [[5ihn]] – hSPTA2 SH3 domain (mutant)<br /> | ||
**[[1qkw]] – cSPTA2 SH3 domain (mutant)<br /> | **[[1qkw]] – cSPTA2 SH3 domain (mutant)<br /> | ||
**[[2fot]] - SPTA2+calmodulin – bovine<br /> | **[[2fot]] - SPTA2+calmodulin – bovine<br /> | ||
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**[[1btn]] – mSPTB+inositol phosphate<br /> | **[[1btn]] – mSPTB+inositol phosphate<br /> | ||
**[[2spc]] – SPT fragment - ''Drosophila melanogaster'' | **[[2spc]] – SPT fragment - ''Drosophila melanogaster'' | ||
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| + | * Spectrin R16 | ||
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| + | **[[3e5m6s]] – SPT - ''Escherichia coli''<br /> | ||
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}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 22:58, 4 October 2017
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3D Structures of Spectrin
Updated on 04-October-2017
References
- ↑ Das A, Base C, Dhulipala S, Dubreuil RR. Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. J Cell Biol. 2006 Oct 23;175(2):325-35. PMID:17060500 doi:http://dx.doi.org/10.1083/jcb.200602095
- ↑ Coetzer T, Palek J, Lawler J, Liu SC, Jarolim P, Lahav M, Prchal JT, Wang W, Alter BP, Schewitz G, et al.. Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis. Blood. 1990 Jun 1;75(11):2235-44. PMID:2346784
- ↑ Dhermy D, Galand C, Bournier O, Cynober T, Mechinaud F, Tchemia G, Garbarz M. Hereditary spherocytosis with spectrin deficiency related to null mutations of the beta-spectrin gene. Blood Cells Mol Dis. 1998 Jun;24(2):251-61. PMID:9714702 doi:http://dx.doi.org/10.1006/bcmd.1998.0190
