Sphingomyelinase
From Proteopedia
(Difference between revisions)
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<StructureSection load='1zwx' size='350' side='right' caption='Sphingomyelinase complex with glycerol and phosphate ion (PDB entry [[21zwx])' scene=''> | <StructureSection load='1zwx' size='350' side='right' caption='Sphingomyelinase complex with glycerol and phosphate ion (PDB entry [[21zwx])' scene=''> | ||
== Function == | == Function == | ||
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**[[2uyr]] – BcSMase (mutant)<br /> | **[[2uyr]] – BcSMase (mutant)<br /> | ||
**[[3wcx]] – SMase C – ''Streptomyces griseocarneus''<br /> | **[[3wcx]] – SMase C – ''Streptomyces griseocarneus''<br /> | ||
| + | **[[5uvg]] – hSMase catalytic domain – human<br /> | ||
*Acid SMase | *Acid SMase | ||
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**[[5fi9]] – mSMase + inhibitor<br /> | **[[5fi9]] – mSMase + inhibitor<br /> | ||
**[[5fic]] – mSMase + lipid<br /> | **[[5fic]] – mSMase + lipid<br /> | ||
| - | **[[5jg8]] – hSMase – | + | **[[5jg8]], [[5i81]], [[5i8r]] – hSMase <br /> |
| + | **[[5i85]] – hSMase + phosphocholine<br /> | ||
| + | |||
| + | *Acid SMase-like phosphodiesterase | ||
| + | |||
| + | **[[5fc1]], [[5fc7]], [[5fca]] – mSMase 3A<br /> | ||
| + | **[[5fcb]] – mSMase 3A + AMP<br /> | ||
| + | **[[5fc6]] – mSMase 3A + AMPCP<br /> | ||
| + | **[[5fc5]] – mSMase 3A + phosphocholine<br /> | ||
| + | **[[5ebb]] – hSMase 3A<br /> | ||
| + | **[[5ebe]] – hSMase 3A + CMP<br /> | ||
| + | **[[5kar]] – mSMase 3B<br /> | ||
| + | **[[5kas]] – mSMase 3B + phosphocholine<br /> | ||
| + | |||
| + | *Alkaline SMase | ||
| + | |||
| + | **[[5udy]] – hSMase <br /> | ||
| + | **[[5tcd]] – hSMase + phosphocholine<br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 18:05, 5 October 2017
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3D structures of sphingomyelinase
Updated on 05-October-2017
References
- ↑ Chatterjee S. Neutral sphingomyelinase: past, present and future. Chem Phys Lipids. 1999 Nov;102(1-2):79-96. PMID:11001563
- ↑ Wasserstein MP, Aron A, Brodie SE, Simonaro C, Desnick RJ, McGovern MM. Acid sphingomyelinase deficiency: prevalence and characterization of an intermediate phenotype of Niemann-Pick disease. J Pediatr. 2006 Oct;149(4):554-9. PMID:17011332 doi:http://dx.doi.org/10.1016/j.jpeds.2006.06.034
