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5iuf
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Bacillus NanoRNase A active site mutant bound to pAp== | |
| + | <StructureSection load='5iuf' size='340' side='right' caption='[[5iuf]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5iuf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IUF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IUF FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ipp|5ipp]]</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3'(2'),5'-bisphosphate_nucleotidase 3'(2'),5'-bisphosphate nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.7 3.1.3.7] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iuf OCA], [http://pdbe.org/5iuf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iuf RCSB], [http://www.ebi.ac.uk/pdbsum/5iuf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iuf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NRNA_BACSU NRNA_BACSU]] Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction (PubMed:17586819), and 11-mers in a 5' to 3' direction (PubMed:21087930). Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.<ref>PMID:17586819</ref> <ref>PMID:21087930</ref> <ref>PMID:22114320</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ribonuclease|Ribonuclease]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Malhotra, A]] | ||
| + | [[Category: Nelersa, C M]] | ||
| + | [[Category: Schmier, B J]] | ||
| + | [[Category: Abortive transcript]] | ||
| + | [[Category: B. subtili]] | ||
| + | [[Category: Exonuclease]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nanorna]] | ||
| + | [[Category: Pap phosphatase]] | ||
| + | [[Category: Rna degradation]] | ||
| + | [[Category: Rnase]] | ||
| + | [[Category: X-ray]] | ||
Revision as of 07:09, 6 October 2017
Bacillus NanoRNase A active site mutant bound to pAp
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