5l1n
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Pyrococcus horikoshii CoA Disulfide Reductase Quadruple Mutant== | |
| - | + | <StructureSection load='5l1n' size='340' side='right' caption='[[5l1n]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5l1n]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L1N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L1N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CoA-disulfide_reductase CoA-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.14 1.8.1.14] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l1n OCA], [http://pdbe.org/5l1n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l1n RCSB], [http://www.ebi.ac.uk/pdbsum/5l1n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l1n ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CDR_PYRHO CDR_PYRHO]] Acts as a coenzyme A disulfide reductase. Specific for CoA disulfide. Shows a slow NAD(P)H oxidase activity in the presence of high concentrations of substrate-level FAD. This demonstrates that it is not likely to act as an NADH oxidase in vivo. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: CoA-disulfide reductase]] | ||
| + | [[Category: Chen, B]] | ||
| + | [[Category: III, E J.Crane]] | ||
| + | [[Category: Sazinsky, M H]] | ||
| + | [[Category: Sea, K]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Sulfur metabolism half-sites reactivity]] | ||
Revision as of 10:34, 7 October 2017
Pyrococcus horikoshii CoA Disulfide Reductase Quadruple Mutant
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