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5svb
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase AMP bound structure== | |
| - | + | <StructureSection load='5svb' size='340' side='right' caption='[[5svb]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5svb]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SVB FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetone_carboxylase Acetone carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.6 6.4.1.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5svb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5svb OCA], [http://pdbe.org/5svb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5svb RCSB], [http://www.ebi.ac.uk/pdbsum/5svb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5svb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACXB_XANP2 ACXB_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXC_XANP2 ACXC_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXA_XANP2 ACXA_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acetone carboxylase]] | ||
| + | [[Category: Alleman, A B]] | ||
| + | [[Category: Dubois, J L]] | ||
| + | [[Category: Eilers, B J]] | ||
| + | [[Category: Kabasakal, B V]] | ||
| + | [[Category: Murray, J W]] | ||
| + | [[Category: Mus, F]] | ||
| + | [[Category: Nocek, B P]] | ||
| + | [[Category: Peters, J W]] | ||
| + | [[Category: Acetoacetate]] | ||
| + | [[Category: Amp]] | ||
| + | [[Category: Atp]] | ||
| + | [[Category: Ligase]] | ||
| + | [[Category: Manganese]] | ||
| + | [[Category: Zinc]] | ||
Revision as of 10:49, 7 October 2017
Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase AMP bound structure
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Categories: Acetone carboxylase | Alleman, A B | Dubois, J L | Eilers, B J | Kabasakal, B V | Murray, J W | Mus, F | Nocek, B P | Peters, J W | Acetoacetate | Amp | Atp | Ligase | Manganese | Zinc
