This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5svc
From Proteopedia
(Difference between revisions)
m (Protected "5svc" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase nucleotide-free structure== | |
| - | + | <StructureSection load='5svc' size='340' side='right' caption='[[5svc]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5svc]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5SVC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5svb|5svb]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetone_carboxylase Acetone carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.4.1.6 6.4.1.6] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5svc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5svc OCA], [http://pdbe.org/5svc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5svc RCSB], [http://www.ebi.ac.uk/pdbsum/5svc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5svc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACXB_XANP2 ACXB_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXC_XANP2 ACXC_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> [[http://www.uniprot.org/uniprot/ACXA_XANP2 ACXA_XANP2]] Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide.<ref>PMID:9237998</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Acetone carboxylase]] | ||
| + | [[Category: Alleman, A B]] | ||
| + | [[Category: Dubois, J L]] | ||
| + | [[Category: Eilers, B J]] | ||
| + | [[Category: Kabasakal, B V]] | ||
| + | [[Category: Murray, J W]] | ||
| + | [[Category: Mus, F]] | ||
| + | [[Category: Nocek, B P]] | ||
| + | [[Category: Peters, J W]] | ||
| + | [[Category: Acetoacetate]] | ||
| + | [[Category: Ligase]] | ||
Revision as of 10:50, 7 October 2017
Mechanism of ATP-Dependent Acetone Carboxylation, Acetone Carboxylase nucleotide-free structure
| |||||||||||
