Transducin

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Line 32: Line 32:
**[[3v5w]] – bTDN (mutant) + G-protein coupled receptor kinase 2<br />
**[[3v5w]] – bTDN (mutant) + G-protein coupled receptor kinase 2<br />
**[[3psc]], [[3pvu]], [[3pvw]], [[4mk0]] – bTDN + β-adrenergic receptor kinase 1<br />
**[[3psc]], [[3pvu]], [[3pvw]], [[4mk0]] – bTDN + β-adrenergic receptor kinase 1<br />
-
**[[5he0]], [[5he1]], [[5he2]], [[5he3]] – hTDN + β-adrenergic receptor kinase 1 + inhibitor<br />
+
**[[5he0]], [[5he1]], [[5he2]], [[5he3]], [[5ukk]], [[5ukl]], [[5ukm]] – hTDN + β-adrenergic receptor kinase 1 + inhibitor<br />
**[[4pnk]] – TDN hβ + bγ (mutant)+ β-adrenergic receptor kinase 1 + inhibitor<br />
**[[4pnk]] – TDN hβ + bγ (mutant)+ β-adrenergic receptor kinase 1 + inhibitor<br />
**[[2bcj]] – bTDN (mutant) + β-adrenergic receptor kinase 1<br />
**[[2bcj]] – bTDN (mutant) + β-adrenergic receptor kinase 1<br />
Line 48: Line 48:
**[[3sn6]] – TDN bα (mutant) + rβ (mutant) +bγ + endolysine + antibody fragment<br />
**[[3sn6]] – TDN bα (mutant) + rβ (mutant) +bγ + endolysine + antibody fragment<br />
**[[5tdh]] – TDN hα (mutant) + rβ + bγ + GDP<br />
**[[5tdh]] – TDN hα (mutant) + rβ + bγ + GDP<br />
-
 
+
**[[5uz7]] – hTDN + calcitonin receptor + antibody fragment - Cryo EM<br />
 +
**[[5vai]] – TDN hα + rβ + bγ+ glucagon-like peptide + antibody fragment - Cryo EM<br />
}}
}}
== References ==
== References ==

Revision as of 17:26, 11 October 2017

Structure of rat transducin α (deepskyblue), β (green) and γ (gold) subunits complex with GDP (PDB code 1gp2).

Drag the structure with the mouse to rotate

3D structures of transducin

Updated on 11-October-2017

References

  1. Lerea CL, Bunt-Milam AH, Hurley JB. Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina. Neuron. 1989 Sep;3(3):367-76. PMID:2534964
  2. Dryja TP, Hahn LB, Reboul T, Arnaud B. Missense mutation in the gene encoding the alpha subunit of rod transducin in the Nougaret form of congenital stationary night blindness. Nat Genet. 1996 Jul;13(3):358-60. PMID:8673138 doi:http://dx.doi.org/10.1038/ng0796-358

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky, Joel L. Sussman

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