1yi8
From Proteopedia
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|ACTIVITY= | |ACTIVITY= | ||
|GENE= DR1093 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243230 Deinococcus radiodurans R1]) | |GENE= DR1093 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243230 Deinococcus radiodurans R1]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yi8 OCA], [http://www.ebi.ac.uk/pdbsum/1yi8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yi8 RCSB]</span> | ||
}} | }} | ||
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[[Category: Buddha, M R.]] | [[Category: Buddha, M R.]] | ||
[[Category: Crane, B R.]] | [[Category: Crane, B R.]] | ||
| - | [[Category: TRP]] | ||
[[Category: auxiliary tryptophanyl trna synthetase]] | [[Category: auxiliary tryptophanyl trna synthetase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:08:04 2008'' |
Revision as of 22:08, 30 March 2008
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| , resolution 2.1Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | DR1093 (Deinococcus radiodurans R1) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of tryptophanyl trRNA synthetase II from Deinococcus radiodurans in complex with L-Trp
Overview
The most divergent of two tryptophanyl tRNA synthetases (TrpRS II) found in Deinococcus radiodurans interacts with a nitric oxide synthase protein that produces 4-nitro-tryptophan (4-NRP). TrpRS II efficiently charges transfer RNA(Trp) with 4-NRP and 5-hydroxy-tryptophan (5-HRP). The crystal structures of TrpRS II bound to tryptophan and 5-HRP reveal residue substitutions that accommodate modified indoles. A class of auxiliary bacterial TrpRSs conserve this capacity to charge tRNA with nonstandard amino acids.
About this Structure
1YI8 is a Single protein structure of sequence from Deinococcus radiodurans r1. Full crystallographic information is available from OCA.
Reference
Structure and activity of an aminoacyl-tRNA synthetase that charges tRNA with nitro-tryptophan., Buddha MR, Crane BR, Nat Struct Mol Biol. 2005 Mar;12(3):274-5. Epub 2005 Feb 20. PMID:15723076
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