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1dj7

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Revision as of 14:46, 12 October 2017

CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE

Structural highlights

1dj7 is a 2 chain structure with sequence from Aphanocapsa sp. (strain n-1). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	,
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[Q55389_SYNY3] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).[PIRNR:PIRNR000260] [FTRV_SYNY3] FTR is a [4Fe-4S] protein playing a central role in the ferredoxin/thioredoxin regulatory chain. It converts an electron signal (photoreduced ferredoxin) to a thiol signal (reduced thioredoxin) in the regulation of enzymes by reduction of specific disulfide groups. Catalyzes the light-dependent activation of several photosynthetic enzymes (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Light generates reducing equivalents in chloroplasts that are used not only for carbon reduction, but also for the regulation of the activity of chloroplast enzymes by reduction of regulatory disulfides via the ferredoxin:thioredoxin reductase (FTR) system. FTR, the key electron/thiol transducer enzyme in this pathway, is unique in that it can reduce disulfides by an iron-sulfur cluster, a property that is explained by the tight contact of its active-site disulfide and the iron-sulfur center. The thin, flat FTR molecule makes the two-electron reduction possible by forming on one side a mixed disulfide with thioredoxin and by providing on the opposite side access to ferredoxin for delivering electrons.

Redox signaling in chloroplasts: cleavage of disulfides by an iron-sulfur cluster.,Dai S, Schwendtmayer C, Schurmann P, Ramaswamy S, Eklund H Science. 2000 Jan 28;287(5453):655-8. PMID:10649999^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Dai S, Schwendtmayer C, Schurmann P, Ramaswamy S, Eklund H. Redox signaling in chloroplasts: cleavage of disulfides by an iron-sulfur cluster. Science. 2000 Jan 28;287(5453):655-8. PMID:10649999

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1dj7"

@@ Line 1: / Line 1: @@
 ==CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE==
 <StructureSection load='1dj7' size='340' side='right' caption='[[1dj7]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
@@ Line 4: / Line 5: @@
 <table><tr><td colspan='2'>[[1dj7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aphanocapsa_sp._(strain_n-1) Aphanocapsa sp. (strain n-1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ7 FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj7 OCA], [http://pdbe.org/1dj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dj7 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj7 PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj7 OCA], [http://pdbe.org/1dj7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dj7 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj7 ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 27: / Line 28: @@
 </div>
 <div class="pdbe-citations 1dj7" style="background-color:#fffaf0;"></div>
-==See Also==
-*[[Ferredoxin thioredoxin reductase|Ferredoxin thioredoxin reductase]]
 == References ==
 <references/>

1dj7

From Proteopedia

Revision as of 14:46, 12 October 2017

CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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