This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2dcb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==X-ray crystal structure analysis of bovine spleen cathepsin B-CA076 complex== | ==X-ray crystal structure analysis of bovine spleen cathepsin B-CA076 complex== | ||
<StructureSection load='2dcb' size='340' side='right' caption='[[2dcb]], [[Resolution|resolution]] 1.94Å' scene=''> | <StructureSection load='2dcb' size='340' side='right' caption='[[2dcb]], [[Resolution|resolution]] 1.94Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2dcb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DCB FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=76V:N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE'>76V</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=76V:N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE'>76V</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ito|1ito]], [[1qdq|1qdq]], [[2dc6|2dc6]], [[2dc7|2dc7]], [[2dc8|2dc8]], [[2dc9|2dc9]], [[2dca|2dca]], [[2dcc|2dcc]], [[2dcd|2dcd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ito|1ito]], [[1qdq|1qdq]], [[2dc6|2dc6]], [[2dc7|2dc7]], [[2dc8|2dc8]], [[2dc9|2dc9]], [[2dca|2dca]], [[2dcc|2dcc]], [[2dcd|2dcd]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dcb OCA], [http://pdbe.org/2dcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dcb RCSB], [http://www.ebi.ac.uk/pdbsum/2dcb PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dcb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dcb OCA], [http://pdbe.org/2dcb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dcb RCSB], [http://www.ebi.ac.uk/pdbsum/2dcb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dcb ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
| Line 16: | Line 17: | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dcb ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Cathepsin|Cathepsin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bovin]] |
[[Category: Cathepsin B]] | [[Category: Cathepsin B]] | ||
[[Category: Watanabe, D]] | [[Category: Watanabe, D]] | ||
Revision as of 15:46, 12 October 2017
X-ray crystal structure analysis of bovine spleen cathepsin B-CA076 complex
| |||||||||||
Categories: Bovin | Cathepsin B | Watanabe, D | Ca076 | Cathepsin b | Cysteine protease | Ec 3 4.22 1 | Hydrolase
